Results 71 to 80 of about 315,406 (303)

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

FEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Comparative Analysis of Parametric Engine Model and Engine Map Model [PDF]

Mehran University Research Journal of Engineering and Technology, 2015
Two different engine models, parametric engine model and engine map model are employed to analyze the dynamics of an engine during the gear shifting. The models are analyzed under critical transitional manoeuvres to investigate their appropriateness for ...
Zeeshan Ali Memon, Sadiq Ali Shah, Muhammas Saleh Jumani   +2 more
doaj  

Dynamical Transition in Dehydrated Proteins

The Journal of Physical Chemistry Letters
Terahertz time-domain spectroscopy and differential scanning calorimetry were used to study the role of the dynamics of biomolecules decoupled from solvent effects. Lyophilized sucrose exhibited steadily increasing absorption with temperature as anharmonic excitations commenced as the system emerged from a deep minimum of the potential energy landscape
Kölbel, Johanna, Anuschek, Moritz L, Stelzl, Ivonne, Santitewagun, Supawan, Friess, Wolfgang, Zeitler, J Axel   +5 more
openaire   +2 more sources

Dynamical constraints on phase transitions [PDF]

Physical Review C, 2000
language corrections and figure decorations ...
openaire   +3 more sources

Dynamic transition in supercritical iron [PDF]

Scientific Reports, 2014
Recent advance in understanding the supercritical state posits the existence of a new line above the critical point separating two physically distinct states of matter: rigid liquid and non-rigid gas-like fluid. The location of this line, the Frenkel line, remains unknown for important real systems. Here, we map the Frenkel line on the phase diagram of
Fomin, YD, Ryzhov, VN, Tsiok, EN, Brazhkin, VV, Trachenko, K   +4 more
openaire   +4 more sources

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

FEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure, Misaki K. Nishio, Satoru Okuda, Kohji Hotta   +3 more
wiley   +1 more source

B Cell Dynamics and Transitional B Cells in Long COVID

Current Issues in Molecular Biology
Background: Long COVID is characterized by persistent symptoms following acute SARS-CoV-2 infection. This study aims to evaluate immune system markers, including antigen-specific antibodies, B cell subsets, and Th2-related cytokines, in individuals with ...
Zoia R. Korobova, Natalia A. Arsentieva, Natalia E. Liubimova, Oleg K. Batsunov, Anastasia A. Butenko, Albina E. Kokoeva, Natalia G. Kucherenko, Victor A. Kashchenko, Ekaterina V. Boeva, Anna O. Norka, Anastasia A. Knizhnikova, Vadim V. Rassokhin, Nikolay A. Belyakov, Areg A. Totolian   +13 more
doaj   +1 more source

Sectoral composition and macroeconomic dynamics [PDF]

We analyze the transitional dynamics of a model with heterogeneous consumption goods. In this model, convergence is driven by two different forces: the typical diminishing returns to capital and the sectoral change inducing the variation in relative ...
Jaime Alonso-Carrera, Jordi Caballé, Xavier Raurich   +2 more
core  

Fluctuations and Phase Transition Dynamics [PDF]

International Journal of Theoretical Physics, 2000
Kibble and Zurek have provided a unifying causal picture for the appearance of classical defects like cosmic strings or vortices at the onset of phase transitions in relativistic QFT and condensed matter systems respectively. In condensed matter the predictions are partially supported by agreement with experiments in superfluid helium.
openaire   +2 more sources

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source