Results 51 to 60 of about 315,406 (303)
Cancer as a dynamical phase transition [PDF]
Theoretical Biology and Medical Modelling, 2011 AbstractThis paper discusses the properties of cancer cells from a new perspective based on an analogy with phase transitions in physical systems. Similarities in terms of instabilities and attractor states are outlined and differences discussed. While physical phase transitions typically occur at or near thermodynamic equilibrium, a normal-to-cancer ...
Davies, Paul CW +2 more
openaire +3 more sources
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
FEBS Letters, EarlyView.We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
Transition systems and dynamic semantics [PDF]
, 2005 Transition systems over first-order models, first-order theories, and families of first-order models are constructed and examined in relation to dynamic semantics (more specifically, DPL, DRT and Update logic). Going the other direction, first-order models are extracted from transition systems, bringing full circle the connection between static and ...
openaire +1 more source
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Melt-growth dynamics in CdTe crystals
, 2012 We use a new, quantum-mechanics-based bond-order potential (BOP) to reveal melt-growth dynamics and fine-scale defect formation mechanisms in CdTe crystals.
Doty, F. P. +3 more
core +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Quantifying Optimal Growth Policy [PDF]
The optimal mix of growth policies is determined within a comprehensive endogenous growth model. The analysis captures important elements of the tax-transfer system and accounts for transitional dynamics.
Thomas Steger +2 more
core +3 more sources
Electromagnetic Dipole Strength in Transitional Nuclei [PDF]
, 2008 Electromagnetic dipole absorption cross-sections of transitional nuclei with large-amplitude shape fluctuations are calculated in a microscopic way by introducing the concept of Instantaneous Shape Sampling.
A. Bohr +11 more
core +4 more sources
Relational state transition dynamics
The Journal of Logic and Algebraic Programming, 2008 zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Giuseppe Scollo +2 more
openaire +3 more sources
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source