Results 61 to 70 of about 315,406 (303)

Structural ultrafast dynamics of macromolecules: diffraction of free DNA and effect of hydration [PDF]

open access: yes, 2009
Of special interest in molecular biology is the study of structural and conformational changes which are free of the additional effects of the environment.
Lin, Milo M.   +2 more
core   +1 more source

Output and unemployment dynamics in transition [PDF]

open access: yesThe Journal of Policy Reform, 2004
This paper examines transition dynamics in a search economy. We contrast two extreme cases: a completely unexpected reform and a fully anticipated reform. We show that announcing the reform in advance leads to stagnation in anticipation and output cycles after the implementation, that are more volatile than had a reform of identical magnitude been ...
Dehejia, Vivek, Dwyer, Douglas W
openaire   +2 more sources

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

open access: yesFEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel   +13 more
wiley   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Using High-Resolution Hydrodynamic Models to Assess the Environmental Status of Highly Modified Transitional Waters in Salt Marshes

open access: yesHydrology
Effective management of transitional waters requires collaboration between administrative and scientific institutions, in line with the sustainable water management principles established by the Water Framework Directive (WFD, 2000/60/EC).
Cira Buonocore   +9 more
doaj   +1 more source

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

open access: yesFEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas   +3 more
wiley   +1 more source

Influence of climate variability, fire and phosphorus limitation on vegetation structure and dynamics of the Amazon–Cerrado border [PDF]

open access: yesBiogeosciences, 2018
Climate, fire and soil nutrient limitation are important elements that affect vegetation dynamics in areas of the forest–savanna transition. In this paper, we use the dynamic vegetation model INLAND to evaluate the influence of interannual climate ...
E. A. Dionizio   +9 more
doaj   +1 more source

Interface Dynamics at the Depinning Transition [PDF]

open access: yesJournal de Physique I, 1997
To appear in Journal de Physique I, 6 pages, 4 figures included using epfs ...
López, Juan M., Rodríguez, Miguel A.
openaire   +4 more sources

AAA+ protein unfoldases—the Moirai of the proteome

open access: yesFEBS Letters, EarlyView.
AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley   +1 more source

Kent, Lia (2012), The Dynamics of Transitional Justice: International Models and Local Realities in East Timor

open access: yesJournal of Current Southeast Asian Affairs, 2014
Book Review of the monograph: Kent, Lia (2012), The Dynamics of Transitional Justice: International Models and Local Realities in East Timor, Abingdon: Routledge (= Series: Transitional Justice), ISBN: 97804 15504362, 252 ...
Deniz Kocak
doaj  

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