Results 61 to 70 of about 10,131 (252)
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Origins of Super Jupiters: TOI-2145b has a Moderately Eccentric and Nearly Aligned Orbit
The Astronomical JournalSuper Jupiters are giant planets with several Jupiter masses. It remains an open question whether these planets originate with such high masses or grow through collisions.
Jiayin Dong +17 more
doaj +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Hundreds of TESS Exoplanets Might Be Larger than We Thought
The Astrophysical Journal LettersThe radius of a planet is a fundamental parameter that probes its composition and habitability. Precise radius measurements are typically derived from the fraction of starlight blocked when a planet transits its host star.
Te Han +7 more
doaj +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
FEBS Letters, EarlyView.Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source
Differential Rotation of CoRoT Stars and a Kepler Binary Star from Starspot Transit Mapping
The Astrophysical JournalWhile direct magnetic field measurements are rare for slowly rotating stars, spots observed during planetary transits provide a potential indicator of magnetic activity on stellar surfaces.
Adriana Valio +2 more
doaj +1 more source
FEBS Letters, EarlyView.Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source
Surviving in the Hot-Neptune Desert: The Discovery of the Ultrahot Neptune TOI-3261b
The Astronomical JournalThe recent discoveries of Neptune-sized ultra-short-period planets (USPs) challenge existing planet formation theories. It is unclear whether these residents of the Hot Neptune Desert have similar origins to smaller, rocky USPs, or if this discrete ...
Emma Nabbie +47 more
doaj +1 more source
All-inorganic cesium lead iodide perovskite solar cells with stabilized efficiency beyond 15%
Nature Communications, 2018 Black phase cesium lead iodide perovskite is regarded as a promising candidate for solar cells, but it easily transits to undesired yellow phase. Herein, Wang et al. stabilized the black phase using molecular additives to achieve device efficiency beyond
Kang Wang +8 more
doaj +1 more source