Results 61 to 70 of about 55,349 (232)

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

TFAW: wavelet-based signal reconstruction to reduce photometric noise in time-domain surveys

open access: yes, 2018
There have been many efforts to correct systematic effects in astronomical light curves to improve the detection and characterization of planetary transits and astrophysical variability.
del Ser, D., Fors, O., Núñez, J.
core   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Single Transit Detection in Kepler with Machine Learning and Onboard Spacecraft Diagnostics

open access: yesThe Astronomical Journal
Exoplanet discovery at long orbital periods requires reliably detecting individual transits without additional information about the system. Common techniques, like phase folding of light curves and periodogram analysis of radial velocity data, are more ...
Matthew T. Hansen, Jason A. Dittmann
doaj   +1 more source

Review of the AC Overhead Wires, the DC Third Rail and the DC Fourth Rail Transit Lines: Issues and Challenges

open access: yesIEEE Access, 2020
This paper focuses on transits available around the world. AC voltage transits and DC voltage transit are reviewed and compared. Emphasis is given to differences, advantages and disadvantages of voltage supplies and traction types.
Farah Asyikin Abd Rahman   +3 more
doaj   +1 more source

The Transit Light Curve Project. IV. Five Transits of the Exoplanet OGLE-TR-10b

open access: yes, 2006
We present I and B photometry of five distinct transits of the exoplanet OGLE-TR-10b. By modeling the light curves, we find the planetary radius to be R_P = 1.06 +/- 0.08 R_Jup and the stellar radius to be R_S = 1.10 +/- 0.07 R_sun. The uncertainties are
B. Scott Gaudi   +18 more
core   +2 more sources

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

Validating the Orbital Periods of the Coolest TESS Planet Candidates

open access: yesThe Astronomical Journal
When an exoplanet passes in front of its host star, the resulting eclipse causes an observable decrease in stellar flux, and when multiple such transits are detected, the orbital period of the exoplanet can be determined. Over the past seven years NASA’s
Dillon J. Bass, Daniel C. Fabrycky
doaj   +1 more source

Observations of planetary transits at the University Observatory Jena

open access: yesEPJ Web of Conferences, 2011
We report on observations of transit events of the transiting planets XO-1b, TrES-1 and TrES-2 with a 25 cm telescope of the University Observatory Jena.
Rammo W.   +16 more
doaj   +1 more source

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