Results 111 to 120 of about 321,646 (309)

Eight new Innovation Awards to explore Translating Cultures

open access: yes, 2014
Date: 02/10/2014 Source: http://www.ahrc.ac.uk/News-and-Events/News/Pages/Eight-new-Innovation-Awards-to-explore-Translating-Cultures.aspx In a world increasingly characterized by globalized connections, the need to understand communication within and ...
Charles Forsdick
core  

Cross-cultural adaptation and validation of the International Cooperative Ataxia Rating Scale (ICARS) to Brazilian Portuguese

open access: yesArquivos de Neuro-Psiquiatria
Introduction: The clinical assessment of patients with ataxias requires reliable scales. We aimed to translate, adapt and validate the International Cooperative Ataxia Rating Scale (ICARS) into Brazilian Portuguese. Methods: The steps of this study were
Fernanda Aparecida Maggi   +9 more
doaj   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

Validity and Reliability of the International Consultation on Incontinence Questionnaire-Urinary Incontinence Short Form and Its Correlation With Urodynamic Findings

open access: yesUrology Journal, 2012
Purpose: To validate the Persian version of the International Consultation on Incontinence Questionnaire-Urinary Incontinence Short Form (ICIQ-UI SF) as a standard questionnaire for assessment of urinary incontinence (UI).Materials and Methods: After ...
Sakineh Hajebrahimi   +3 more
doaj  

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

open access: yesFEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg   +14 more
wiley   +1 more source

West African Literature and Thought in French: Translating Cultures

open access: yes, 2015
West African Literature and Thought in French: Translating Cultures Friday 22 January 2016, British Library Conference Centre, 10-30-17.00 Some of the most important contemporary writing in French has emerged from West Africa.
Charles Forsdick
core  

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

open access: yesFEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas   +4 more
wiley   +1 more source

Epigenetic reprogramming of lineage switching in cancer

open access: yesFEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı   +4 more
wiley   +1 more source

Validation of a culturally adapted Malay theory of planned behavior scale to assess mental health help-seeking intention among Malaysian individuals with breast cancer

open access: yesJournal of Education and Health Promotion
INTRODUCTION: Psychological distress is highly prevalent among individuals with breast cancer (BC). This study culturally adapted the theory of planned behavior (TPB) scale and translated it into the Malay language to validate its evaluation of mental ...
Nurdiana Mohammad Hussin   +3 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

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