Results 121 to 130 of about 321,646 (309)

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

Translating Development

open access: yes, 2017
A free seminar with the support of the AHRC and the Institute of Modern Languages Research (IMLR) October 12th, Senate House, London: 1-4 This seminar will provide a forum for translators working in the area of development and NGOs to talk about their ...
Charles Forsdick
core   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Interpretive use: translating intensification

open access: yes, 2001
My aim here is to discuss first the fitness of a cognitive theory like RT when approaching the interpretive operations taking place in the translating activity. The basic notion of interpretive resemblance is put forward instead of the traditional one of
López Folgado, Vicente
core  

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Translating the Poetry of the Holocaust:Translation, Style and the Reader

open access: yes, 2015
Taking a cognitive approach, this book asks what poetry, and in particular Holocaust poetry, does to the reader - and to what extent the translation of this poetry can have the same effects.
Boase-Beier, Jean
core  

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

Translating Serbian regional verbs into English : The southern dialect and phonaesthetic properties

open access: yes, 2013
The paper investigates the ways in which Serbian regional verbs, particularly the ones coming from the south of the country, are translated into English.
Tasić, Miloš,, Stamenković, Dušan,
core  

Translating rage [PDF]

open access: yes, 2014
Two women stand either side of a screen and give a lecture. Projected on the screen behind them is a series of changing words. These words, abusive, vulgar, shocking and angry suggest an anger the historic etymology give meaning to the terms beyond the ...
Bartram, A., Mary O'Neill
core  

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