Results 141 to 150 of about 5,388,665 (365)

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

Molecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son, Lily L. Remsing Rix, Bin Fang, Eric A. Welsh, Nicole V. Bremer, Valentina Foglizzo, Paola Roa, Nickole Sigcha‐Coello, Yi Liao, Eric B. Haura, Alexander Drilon, John M. Koomen, Emiliano Cocco, Uwe Rix   +13 more
wiley   +1 more source

The neglected association between schizophrenia and bone fragility: a systematic review and meta-analyses

Translational Psychiatry
Schizophrenia is associated with increased risk of medical comorbidity, possibly including osteoporosis, which is a public health concern due to its significant social and health consequences.
Behnaz Azimi Manavi, Kayla B. Corney, Mohammadreza Mohebbi, Shae E. Quirk, Amanda L. Stuart, Julie A. Pasco, Jason M. Hodge, Michael Berk, Lana J. Williams   +8 more
doaj   +1 more source

Selective translation by alternative bacterial ribosomes [PDF]

, 2020
Yuxiang Chen, Zhiyu Xu, Xueliang Ge, Jia-Yao Hong, Suparna Sanyal, Zhi John Lu, Babak Javid   +6 more
openalex   +1 more source

A retrospective view on the promise on machine translation for Bahasa Melayu-English [PDF]

, 2010
Research and development activities for machine translation systems from English language to others are more progressive than vice versa. It has been more than 30 years since the machine translation was introduced and yet a Malay language or Bahasa ...
Jamaludin, Zulikha, Jusoh, Shaidah, Mohd Noor, Yusnita   +2 more
core  

Molecular characterisation of human penile carcinoma and generation of paired epithelial primary cell lines

Molecular Oncology, EarlyView.
Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad, Mahmood Hachim, Tom Bertin, Karolina Penderecka, Rifat Hamoudi, Saif Khan, Rui Henrique, Natalie Bergmoser, Manit Arya, Kalle Sipila, Matteo Vietri Rudan, Asif Muneer, Aamir Ahmed   +12 more
wiley   +1 more source

Establishing Effective Patient Engagement Through a Terms of Reference to Foster Inclusivity and Empowerment in Research: Example From a Healthcare Transition Quality Indicators Project

Health Expectations
Introduction Patient engagement in research aims to foster meaningful partnerships, integrating patient experiences into the research process. This paper describes the development of a Terms of Reference (ToR) to support these meaningful partnerships ...
Sarah E. P. Munce, Tomisin John, Dorothy Luong, Sarah Mooney, Lisa Stromquist, Kyle Chambers, Marilyn Crabtree, Sanober Diaz, Gina Dimitropoulos, Megan Henze, Amanda Higgins, Elaine Li, Samadhi Mora Severino, Melanie Penner, Jacklynn Pidduck, Michelle Wan, Laura Williams, Darryl Yates, Alene Toulany   +18 more
doaj   +1 more source

DDX21, a Host Restriction Factor of FMDV IRES-Dependent Translation and Replication [PDF]

, 2021
Sahibzada Waheed Abdullah, Jin’en Wu, Yun Zhang, Manyuan Bai, Junyong Guan, Xiangtao Liu, Shiqi Sun, Huichen Guo   +7 more
openalex   +1 more source

Case Translation: Germany [PDF]

Ur19 U 16/02, OLG Köln, 6 September 2002.
Case Translation:, Germany
core  

Cis‐regulatory and long noncoding RNA alterations in breast cancer – current insights, biomarker utility, and the critical need for functional validation

Molecular Oncology, EarlyView.
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués, Aracele Martinez‐Mendez, John Crown, Alex Eustace   +3 more
wiley   +1 more source

The translatics of translation

Journal of Modern Languages, 2017
The project on which this paper is based offers Translatics as a theory of translation which is designed and developed as an alternative that challenges the mainstream views currently held within translation studies. To familiarize the readers with Translatics, an attempt will be made to provide and describe its foundational key concepts and features ...
openaire   +8 more sources