Results 141 to 150 of about 5,278,373 (369)

Circulating tumor DNA monitoring and blood tumor mutational burden in patients with metastatic solid tumors treated with atezolizumab

open access: yesMolecular Oncology, EarlyView.
In patients treated with atezolizumab as a part of the MyPathway (NCT02091141) trial, pre‐treatment ctDNA tumor fraction at high levels was associated with poor outcomes (radiographic response, progression‐free survival, and overall survival) but better sensitivity for blood tumor mutational burden (bTMB).
Charles Swanton   +17 more
wiley   +1 more source

Dose‐dependent induction of epithelial‐mesenchymal transition in 3D melanoma models by non‐thermal plasma treatment

open access: yesMolecular Oncology, EarlyView.
Non‐thermal plasma treatment of melanoma cells induced epithelial‐mesenchymal transition (EMT) in a dose‐dependent fashion. This report highlights the critical need to further investigate potential adverse effects of non‐thermal plasma for cancer therapy and to optimize treatment parameters for clinical translation. Despite the promising results of non‐
Eline Biscop   +10 more
wiley   +1 more source

Intrinsic managing and the English-Arabic translation of fictional registers

open access: yesCogent Arts & Humanities
The translation process involves several changes made to the source text. Some of these changes, referred to as intrinsic managing , are necessary to overcome linguistic differences and create a cohesive, coherent, and natural text without altering the ...
Hadeel Saed   +3 more
doaj   +1 more source

Building a resource for studying translation shifts [PDF]

open access: yes, 2006
This paper describes an interdisciplinary approach which brings together the fields of corpus linguistics and translation studies. It presents ongoing work on the creation of a corpus resource in which translation shifts are explicitly annotated ...
Cyrus, Lea
core   +2 more sources

Genomics‐led approach to drug testing in models of undifferentiated pleomorphic sarcoma

open access: yesMolecular Oncology, EarlyView.
GA text Genomic data from undifferentiated pleomorphic sarcoma patients and preclinical models were used to inform a targeted drug screen. Selected compounds were tested in 2D and 3D cultures of UPS cell lines. A combination of trametinib and infigratinib was synergistic in the majority of UPS cell lines tested, which was further confirmed in an ex ...
Piotr J. Manasterski   +19 more
wiley   +1 more source

Teaching machine translation and translation technology: a contrastive study [PDF]

open access: yes, 2001
The Machine Translation course at Dublin City University is taught to undergraduate students in Applied Computational Linguistics, while Computer-Assisted Translation is taught on two translator-training programmes, one undergraduate and one ...
Kenny, Dorothy, Way, Andy
core  

Unraveling LINE‐1 retrotransposition in head and neck squamous cell carcinoma

open access: yesMolecular Oncology, EarlyView.
The novel RetroTest method allows the detection of L1 activation in clinical samples with low DNA input, providing global L1 activity and the identification of the L1 source element. We applied RetroTest to a real‐world cohort of HNSCC patients where we reported an early L1 activation, with more than 60% of T1 patients showing L1 activity.
Jenifer Brea‐Iglesias   +12 more
wiley   +1 more source

Translations and quasi-translations in E3

open access: yesGeneral Topology and its Applications, 1972
AbstractA homeomorphism h of Euclidean space onto itself is a quasi-translation if h is regular at each point and the extension of h to the one-point compactification fails to be regular at ∞. Necessary and sufficient conditions are given for a quasi-translation to be topologically equivalent to the translation of three dimensional Euclidean space ...
W.H. Row, L.S. Husch
openaire   +3 more sources

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