Results 41 to 50 of about 925,579 (306)
Adaptive laboratory evolution of a genome-reduced Escherichia coli. [PDF]
, 2019 Synthetic biology aims to design and construct bacterial genomes harboring the minimum number of genes required for self-replicable life. However, the genome-reduced bacteria often show impaired growth under laboratory conditions that cannot be ...
Cho, Byung-Kwan +8 more
core +2 more sources
Vaccines, 2023 Heparin-binding hemagglutinin (HBHA) and M. tuberculosis pili (MTP) are important antigens on the surface of Mycobacterium tuberculosis. To display these antigens effectively, the fusion protein HBHA-MTP with a molecular weight of 20 kD (L20) was ...
Juan Wang +11 more
doaj +1 more source
On robust stability of stochastic genetic regulatory networks with time delays: A delay fractioning approach [PDF]
, 2010 Copyright [2009] IEEE. This material is posted here with permission of the IEEE. Such permission of the IEEE does not in any way imply IEEE endorsement of any of Brunel University's products or services.
Liang, J, Wang, Y, Wang, Z
core +1 more source
Reciprocal control of viral infection and phosphoinositide dynamics
FEBS Letters, EarlyView.Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
Technological advancements in antibody-based therapeutics for treatment of diseases
Journal of Biomedical ScienceMonoclonal antibodies (mAbs) represent a major class of therapeutics with widespread clinical applications in oncology, immunology, hematology, neurology and infectious disease.
Ruei-Min Lu +14 more
doaj +1 more source
On the Ribosomal Density that Maximizes Protein Translation Rate. [PDF]
PLoS ONE, 2016 During mRNA translation, several ribosomes attach to the same mRNA molecule simultaneously translating it into a protein. This pipelining increases the protein translation rate.
Yoram Zarai +2 more
doaj +1 more source
FEBS Letters, EarlyView.Phototrophs evolved light‐harvesting systems adapted for efficient photon capture in habitats enriched in far‐red radiation. A subset of eukaryotic pigment‐binding proteins can absorb far‐red photons via low‐energy chlorophyll states known as red forms.
Antonello Amelii +8 more
wiley +1 more source
Caloric Restriction Induces MicroRNAs to Improve Mitochondrial Proteostasis
iScience, 2019 Summary: Both caloric restriction (CR) and mitochondrial proteostasis are linked to longevity, but how CR maintains mitochondrial proteostasis in mammals remains elusive. MicroRNAs (miRNAs) are well known for gene silencing in cytoplasm and have recently
Ran Zhang +17 more
doaj +1 more source
A Unifying Scenario on the Origin and Evolution of Cellular and Viral Domains [PDF]
, 2009 The cellular theory on the nature of life has been one of the first major advancements in biology. Viruses, however, are the most abundant life forms, and their exclusion from mainstream biology and the Tree of Life (TOL) is a major paradox in biology ...
Claudiu I. Bandea
core +1 more source
Positional proteomics reveals differences in N-terminal proteoform stability [PDF]
, 2016 To understand the impact of alternative translation initiation on a proteome, we performed a proteome-wide study on protein turnover using positional proteomics and ribosome profiling to distinguish between N-terminal proteoforms of individual genes.
Brown JL +4 more
core +2 more sources