Results 51 to 60 of about 2,991,765 (400)
Frontiers in Immunology, 2022 Boosting Bacillus Calmette-Guérin (BCG) with subunit vaccine is expected to induce long-term protection against tuberculosis (TB). However, it is urgently needed to optimize the boosting schedule of subunit vaccines, which consists of antigens from or ...
Wei Lv +12 more
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Translation of Anticancer Efficacy From Nonclinical Models to the Clinic [PDF]
, 2014 Mouse cancer models have provided critical insights into tumor biology; however, clinical translation of these findings has been challenging. This perspective posits that factors impacting on successful translation start with limitations in capturing ...
Duda, D G +4 more
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Miniaturizing chemistry and biology using droplets in open systems
Nature Reviews Chemistry, 2023 Open droplet microfluidic systems manipulate droplets on the picolitre-to-microlitre scale in an open environment. They combine the compartmentalization and control offered by traditional droplet-based microfluidics with the accessibility and ease-of-use
Yuting Zeng +7 more
semanticscholar +1 more source
“Translational” Legume Biology. Models to Crops [PDF]
Plant Physiology, 2005 The last twenty years have been a period of rapid advance in our understanding of plant biology, metabolism, and genomics. In large part, these advances were facilitated by adoption of plant models, the first and most important being Arabidopsis thaliana.
Gary Stacey, Kate VandenBosch
openaire +2 more sources
Cell Reports, 2017 Summary: Genetic alterations impacting ubiquitously expressed proteins involved in RNA metabolism often result in neurodegenerative conditions, with increasing evidence suggesting that translation defects can contribute to disease.
Paola Bernabò +14 more
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New Perspectives on Reverse Translation: Brief History and Updates
Universitas Scientiarum, 2023 Since the 1950s, reverse translation has been an enigmatic part of Crick’s central dogma of molecular biology. It might be described as the possibility to back-translate information from proteins to nucleic acids (or codons).
Adhityo Wicaksono +2 more
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Nanotechnology and cancer [PDF]
, 2008 The biological picture of cancer is rapidly advancing from models built from phenomenological descriptions to network models derived from systems biology, which can capture the evolving pathophysiology of the disease at the molecular level.
Davis, Mark E., Heath, James R.
core +2 more sources
The biology of frailty in humans and animals: Understanding frailty and promoting translation
Aging Medicine, 2019 Frailty is a state of high vulnerability to adverse health outcomes. This concept is used to explain the heterogeneity in rates of aging in people of the same age.
E. Bisset, S. Howlett
semanticscholar +1 more source
Translational opportunities of single-cell biology in atherosclerosis
European Heart Journal, 2022 AbstractThe advent of single-cell biology opens a new chapter for understanding human biological processes and for diagnosing, monitoring, and treating disease. This revolution now reaches the field of cardiovascular disease (CVD). New technologies to interrogate CVD samples at single-cell resolution are allowing the identification of novel cell ...
de Winther, Menno P J +16 more
openaire +3 more sources
Building the UK's industrial base in engineering biology
Engineering Biology, 2021 The paper describes the strategy and components that have been put in place to build the UK's research and industrial base in Engineering Biology. The initial section of the paper provides a brief historical overview of the development of the field in ...
Richard I. Kitney
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