Results 51 to 60 of about 2,935,766 (379)

“Translational” Legume Biology. Models to Crops [PDF]

open access: yesPlant Physiology, 2005
The last twenty years have been a period of rapid advance in our understanding of plant biology, metabolism, and genomics. In large part, these advances were facilitated by adoption of plant models, the first and most important being Arabidopsis thaliana.
Gary Stacey, Kate VandenBosch
openaire   +2 more sources

Nanotechnology and cancer [PDF]

open access: yes, 2008
The biological picture of cancer is rapidly advancing from models built from phenomenological descriptions to network models derived from systems biology, which can capture the evolving pathophysiology of the disease at the molecular level.
Davis, Mark E., Heath, James R.
core   +2 more sources

Miniaturizing chemistry and biology using droplets in open systems

open access: yesNature Reviews Chemistry, 2023
Open droplet microfluidic systems manipulate droplets on the picolitre-to-microlitre scale in an open environment. They combine the compartmentalization and control offered by traditional droplet-based microfluidics with the accessibility and ease-of-use
Yuting Zeng   +7 more
semanticscholar   +1 more source

A booster dose of Delta × Omicron hybrid mRNA vaccine produced broadly neutralizing antibody against Omicron and other SARS-CoV-2 variants

open access: yesJournal of Biomedical Science, 2022
Background With the continuous emergence of new SARS-CoV-2 variants that feature increased transmission and immune escape, there is an urgent demand for a better vaccine design that will provide broader neutralizing efficacy.
I-Jung Lee   +40 more
doaj   +1 more source

New Perspectives on Reverse Translation: Brief History and Updates

open access: yesUniversitas Scientiarum, 2023
Since the 1950s, reverse translation has been an enigmatic part of Crick’s central dogma of molecular biology. It might be described as the possibility to back-translate information from proteins to nucleic acids (or codons).
Adhityo Wicaksono   +2 more
doaj   +1 more source

Characterization and Potential Applications of Dog Natural Killer Cells in Cancer Immunotherapy. [PDF]

open access: yes, 2019
Natural killer (NK) cells of the innate immune system are a key focus of research within the field of immuno-oncology based on their ability to recognize and eliminate malignant cells without prior sensitization or priming.
Canter, Robert J   +2 more
core   +2 more sources

The biology of frailty in humans and animals: Understanding frailty and promoting translation

open access: yesAging Medicine, 2019
Frailty is a state of high vulnerability to adverse health outcomes. This concept is used to explain the heterogeneity in rates of aging in people of the same age.
E. Bisset, S. Howlett
semanticscholar   +1 more source

In Vivo Translatome Profiling in Spinal Muscular Atrophy Reveals a Role for SMN Protein in Ribosome Biology

open access: yesCell Reports, 2017
Summary: Genetic alterations impacting ubiquitously expressed proteins involved in RNA metabolism often result in neurodegenerative conditions, with increasing evidence suggesting that translation defects can contribute to disease.
Paola Bernabò   +14 more
doaj   +1 more source

Optimizing the Boosting Schedule of Subunit Vaccines Consisting of BCG and “Non-BCG” Antigens to Induce Long-Term Immune Memory

open access: yesFrontiers in Immunology, 2022
Boosting Bacillus Calmette-Guérin (BCG) with subunit vaccine is expected to induce long-term protection against tuberculosis (TB). However, it is urgently needed to optimize the boosting schedule of subunit vaccines, which consists of antigens from or ...
Wei Lv   +12 more
doaj   +1 more source

Translation of Anticancer Efficacy From Nonclinical Models to the Clinic [PDF]

open access: yes, 2014
Mouse cancer models have provided critical insights into tumor biology; however, clinical translation of these findings has been challenging. This perspective posits that factors impacting on successful translation start with limitations in capturing ...
Duda, D G   +4 more
core   +1 more source

Home - About - Disclaimer - Privacy