Results 51 to 60 of about 2,935,766 (379)
“Translational” Legume Biology. Models to Crops [PDF]
The last twenty years have been a period of rapid advance in our understanding of plant biology, metabolism, and genomics. In large part, these advances were facilitated by adoption of plant models, the first and most important being Arabidopsis thaliana.
Gary Stacey, Kate VandenBosch
openaire +2 more sources
Nanotechnology and cancer [PDF]
The biological picture of cancer is rapidly advancing from models built from phenomenological descriptions to network models derived from systems biology, which can capture the evolving pathophysiology of the disease at the molecular level.
Davis, Mark E., Heath, James R.
core +2 more sources
Miniaturizing chemistry and biology using droplets in open systems
Open droplet microfluidic systems manipulate droplets on the picolitre-to-microlitre scale in an open environment. They combine the compartmentalization and control offered by traditional droplet-based microfluidics with the accessibility and ease-of-use
Yuting Zeng+7 more
semanticscholar +1 more source
Background With the continuous emergence of new SARS-CoV-2 variants that feature increased transmission and immune escape, there is an urgent demand for a better vaccine design that will provide broader neutralizing efficacy.
I-Jung Lee+40 more
doaj +1 more source
New Perspectives on Reverse Translation: Brief History and Updates
Since the 1950s, reverse translation has been an enigmatic part of Crick’s central dogma of molecular biology. It might be described as the possibility to back-translate information from proteins to nucleic acids (or codons).
Adhityo Wicaksono+2 more
doaj +1 more source
Characterization and Potential Applications of Dog Natural Killer Cells in Cancer Immunotherapy. [PDF]
Natural killer (NK) cells of the innate immune system are a key focus of research within the field of immuno-oncology based on their ability to recognize and eliminate malignant cells without prior sensitization or priming.
Canter, Robert J+2 more
core +2 more sources
The biology of frailty in humans and animals: Understanding frailty and promoting translation
Frailty is a state of high vulnerability to adverse health outcomes. This concept is used to explain the heterogeneity in rates of aging in people of the same age.
E. Bisset, S. Howlett
semanticscholar +1 more source
Summary: Genetic alterations impacting ubiquitously expressed proteins involved in RNA metabolism often result in neurodegenerative conditions, with increasing evidence suggesting that translation defects can contribute to disease.
Paola Bernabò+14 more
doaj +1 more source
Boosting Bacillus Calmette-Guérin (BCG) with subunit vaccine is expected to induce long-term protection against tuberculosis (TB). However, it is urgently needed to optimize the boosting schedule of subunit vaccines, which consists of antigens from or ...
Wei Lv+12 more
doaj +1 more source
Translation of Anticancer Efficacy From Nonclinical Models to the Clinic [PDF]
Mouse cancer models have provided critical insights into tumor biology; however, clinical translation of these findings has been challenging. This perspective posits that factors impacting on successful translation start with limitations in capturing ...
Duda, D G+4 more
core +1 more source