Results 101 to 110 of about 8,994,214 (249)

Combining multi-domain statistical machine translation models using automatic classifiers [PDF]

open access: yes, 2010
This paper presents a set of experiments on Domain Adaptation of Statistical Machine Translation systems. The experiments focus on Chinese-English and two domain-specific corpora. The paper presents a novel approach for combining multiple domain-trained
Li, Baoli   +5 more
core   +2 more sources

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim   +17 more
wiley   +1 more source

Children on steps of Ohio History Center

open access: yes, 1970
This photograph of children on the steps of the Ohio History Center was taken around 1970. At a press conference held in November 10, 1964, Governor James Rhodes announced financing for the construction of a new archives, library, and museum building ...
Ohio History Connection
core  

Nodes of Translation: Intellectual History Between Modern India and Germany

open access: yes
Book Review: Christof-Füchsle, Martin, and Razak Khan, eds. Nodes of Translation: Intellectual History Between Modern India and Germany.
Kumar Sharma, Amit
core   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

open access: yesFEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová   +2 more
wiley   +1 more source

Transcripts enriched in codons that trigger P‐site tRNA‐mediated mRNA decay possess stable mRNA

open access: yesFEBS Open Bio, EarlyView.
PTMD codons were first described by Mendel et al. as mediators of an mRNA decay pathway dependent on the human protein CNOT3, homologous to yeast Not5. Our findings confirm that PTMD codons destabilize transcripts; however, unlike in yeast, the human pathway specifically targets and slightly destabilizes primarily stable mRNAs.
Rodolfo Lopes Carneiro   +1 more
wiley   +1 more source

Ohio History Center Dedication Ceremony photograph

open access: yes, 1970
This 9.5" x 6.5" (24.13 x 16.51cm) photograph of the dedication of the Ohio History Center, the new home of the Ohio Historical Society (now the Ohio History Connection), was taken on August 23, 1970.
Ohio History Connection
core  

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

open access: yesFEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya   +2 more
wiley   +1 more source

Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells

open access: yesFEBS Open Bio, EarlyView.
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim   +4 more
wiley   +1 more source

The use of corpora and other electronic tools in historical research on translation [PDF]

open access: yes
[EN] Translation history and historiographical approaches to translation have traditionally relied on the knowledge provided by the historical context and both contextual and paratextual features of the translated texts together with their reception ...
Gómez Castro, Cristina
core   +1 more source

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