Results 61 to 70 of about 90,285 (263)
FEBS Open Bio, EarlyView.Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero +5 more
wiley +1 more source
Research Questions and a Proposal for the Future Governance of Translation Data
JoSTrans: The Journal of Specialised Translation, 2019 This article seeks to assess the impact of data-driven methods of machine translation (MT), not just on translators, but more broadly on industry and society.
Joss Moorkens, Dave Lewis
doaj +1 more source
Translation, from Pen-and-Paper to Computer-Assisted Tools (CAT Tools) and Machine Translation (MT)
Proceedings, 2020 This paper reflects the technology-induced novelty of translation, which is perceived as a bridge between languages and cultures. We debate the extent to which the translation process maintains its specificity in the light of the new technology-enhanced ...
Bianca Han
doaj +1 more source
FEBS Open Bio, EarlyView.Drugs previously repurposed to target blood cancers reduced neuroblastoma and glioblastoma cell growth and viability. However, their levels of anticancer activity were different and their clinical application may be problematic due to side effects at effective doses.
Abhishek Kharawatkar +4 more
wiley +1 more source
Directed evolution of enzymes at the crossroads of tradition and innovation
FEBS Open Bio, EarlyView.An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova +2 more
wiley +1 more source
FEBS Open Bio, EarlyView.Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya +2 more
wiley +1 more source
LE MARCHE DE TRADUCTION AU CANADA ET AU NIGERIA : UNE ENQUETE COMPARATIVE
Belas Infiéis, 2016 In the present age which obviously, is well known for globalization, the fact that the world is growing more and more into a global village where connectivity takes place in real time is no longer debatable.
Olusegun Afolabi
doaj
Translation and Interpreting : the International Journal of Translation and Interpreting Research, 2015 The evolution of the language industry over the last two decades has led to drastic changes in the translation process, the translator professional profile and overall organizational dynamics within the industry.
Mónica Rodríguez-Castro
doaj +1 more source
Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells
FEBS Open Bio, EarlyView.Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim +4 more
wiley +1 more source
industrial process for quality machine translation
The Journal of Specialised Translation, 2013 Machine translation (MT) is not a tool. Machine translation is an industrial process. Selecting the right MT engine – rules-based (RBMT), statistical (SMT) or hybrid – is just one part of a process that, if correctly managed, is capable of lowering translation costs, increasing productivity and even improving quality and consistency. To reach this goal,
openaire +2 more sources