Results 51 to 60 of about 90,285 (263)

Trends in e-tools and resources for translators and interpreters

Translation and Interpreting : the International Journal of Translation and Interpreting Research, 2021
Recent years have witnessed the rapid development of translation technology, which has achieved tremendous success in both academia and industry. Due to these rapid advances, it is clear that technology has already profoundly affected the way translation
Rouhullah Nemati Parsa
doaj   +1 more source

Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma

Molecular Oncology, EarlyView.
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski, Júlia Perera‐Bel, Alejo Rodriguez‐Vida, Nuria Juanpere, Jihyun Lee, Daniel E. Michaud, Jennifer L. Guerriero, Kent W. Mouw, Aristotelis Bamias, Filipe L. F. Carvalho, Joaquim Bellmunt   +10 more
wiley   +1 more source

Inhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation

Molecular Oncology, EarlyView.
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington, Divya L. Dayanidhi, Mohammad Zokaasadi, John B. Mantyh, Pelumi D. Olawuni, Gabrielle Rupprecht, Jeremy M. Force, Shannon McCall, Ashwani K. Bahl, David S. Hsu, Jason A. Somarelli   +10 more
wiley   +1 more source

Learned industriousness as a translational mechanism in anorexia nervosa

Nature Reviews Psychology, 2021
Researchers have long grappled to understand the persistence of behaviors that are non-hedonic and, ostensibly, aversive. At times, such behaviors are taken to excess in the form of psychopathology. Anorexia nervosa characterizes a prototype of a disorder in which behaviors that most people find unpleasant (e.g., restrictive eating, excessive exercise)
Ann Frances Haynos, Emily Marie Koithan, Kelsey E. Hagan   +2 more
openaire   +3 more sources

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

Molecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang, Hyung Seok Kim, Geum Ok Baek, Moon Gyeong Yoon, Su In Lee, Jee‐Yeong Jeong, Ji Eun Han, Soon Sun Kim, Jae Youn Cheong, Jung Woo Eun   +9 more
wiley   +1 more source

Translation as an entrepreneurship and an Effective Factor in Small Businesses Growth: Evidence from the Field of Saudi Translation

مجلة العلوم التربوية والدراسات الإنسانية سلسلة الآداب والعلوم التربوية والإنسانية والتطبيقية
This study focuses on the importance of translation as a growing industry sector in Saudi society. It aims at investigating the reality of translation sector as an entrepreneurship, and the role of AI in translation in Saudi Arabia. Using the descriptive
Elghali Mahmoud Seddaig
doaj   +1 more source

YIPFα1A expression is regulated by multilayered molecular mechanisms

FEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji, Yurika Nakanishi, Nobuhiro Nakamura   +2 more
wiley   +1 more source

The impact of an industry-driven translation training program on the performance of trainee translators

Cogent Arts & Humanities
This study reports on a quasi-experimental study on the effect of an industry-driven online translation training program on the translator trainees’ performance across five indicators: language, accuracy, terminology, style and clarity.
Buthainah M. Al Thowaini, Mutahar Qassem
doaj   +1 more source

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

FEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer, Angelique Kragl, Katrin Ziems, Juliane Glaubitz, Sophie Grammbauer, Susanne Hildebrandt, Mladen V. Tzvetkov, Gabriele Jedlitschky   +7 more
wiley   +1 more source

Recent trends in the translation industry in Slovenia

JoSTrans: The Journal of Specialised Translation, 2008
Following two earlier studies, which examined the use of translation tools and the needs of the translation job market, this paper reports on the results of an empirical study into the state of affairs in the Slovene translation industry. A survey of the
Darja Fišer
doaj   +1 more source