Results 41 to 50 of about 90,285 (263)

Translating academic careers into industry healthcare professions [PDF]

Nature Biotechnology, 2020
Though academic institutions have contributed enormously to the remarkable growth in the healthcare industry, a key limiting resource for this continued growth is the creation of career opportunities for doctoral graduates.
Sinje Gehr, Craig C. Garner, Karin N. Kleinhans   +2 more
openaire   +3 more sources

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

The Challenges of Technical Translation: Case Study [PDF]

Ovidius University Annals: Economic Sciences Series, 2016
The aim of this paper is to provide an analysis of the textile industry vocabulary, in order tohighlight the variety of the terms used to describe the respective field and to emphasize thedifficulties that hinder the translation of a specialized text ...
Alina Buzarna-Tihenea (Galbeaza), Lavinia Nadrag   +1 more
doaj  

Defining Translation Quality

Revista Tradumàtica, 2014
Many problems in the translation industry revolve around customer dissatisfaction with someone’s translation quality and disputes between translators when one is revising the work of the other.
Geoffrey S. Koby, Paul Fields, Daryl R. Hague, Arle Lommel, Alan Melby   +4 more
doaj   +1 more source

What experts say about increasingly relevant translation technologies

Revista Tradumàtica, 2022
When the community of translation researchers, trainers and practitioners is asked what they consider to be most relevant as regards translation technology research in the near future, the unanimous answer is neural machine translation (NMT).
Pilar Sánchez-Gijón
doaj   +1 more source

Economic Trends and Developments in the Translation Industry [PDF]

The Interpreter and Translator Trainer, 2007
This paper examines some of the features of the translation services sector, based on economic performance data, industry-specific surveys and developments in the formulation of international standards for translation services. A section of the paper is devoted to each of these aspects.
openaire   +2 more sources

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

Psychological consequences of the digital transformation of the translation industry: an exploratory study of technostress among Danish certified translators

Revista Tradumàtica
Based on survey data, the study explores the consequences of digital transformation for the well-being of Danish certified translators, focusing on the level of technostress related to translators’ adoption of CAT tools, neural machine translation tools
Tina Paulsen Christensen, Kristine Bundgaard, Marian Flanagan   +2 more
doaj   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source