Results 81 to 90 of about 147,255 (350)

Generation of CCR4/CD7 Bispecific CAR‐T Cells Resistant to Fratricide and Exhaustion

open access: yesAdvanced Science, EarlyView.
The applications of CAR T‐cell therapy in T‐cell malignancies face limitations such as fratricide, effector‐cell exhaustion, and antigen‐escape. Herein, we developed fratricide‐ and exhaustion‐resistant CAR‐T cells that targeted CCR4 and CD7 simultaneously, with optional EGFRt safety switch. Additionally, scRNA‐seq unveiled new molecular targets, which
Sile Li   +10 more
wiley   +1 more source

Problem-based Learning in Computer-assisted Translation Pedagogy

open access: yesHermes, 2018
This article discusses problem-based learning (PBL) and its potential application to computer-assisted translation (CAT) pedagogy. Problem-based learning is situated in the CAT classroom as a final course component in which students challenge their ...
Christopher D. Mellinger
doaj   +1 more source

Adult Sex Ratio as a Demographic Feedback Linking Mating Systems, Parental Care, and Evolution

open access: yesAdvanced Science, EarlyView.
Breeding systems are some of the most diverse social behavior, and our team is investigation the evolutionary causes of this diversity. This review summarises our research carried out at the University of Bath. We argue that demographic components of wild populations, especially the adult sex ratio, plays a key role driving breeding system variation ...
Tamás Székely, Oscar G. Miranda
wiley   +1 more source

Language of Translation and Interculturality for a Corpus-based Translation Pedagogy

open access: yesSignata, 2016
With the purpose of devising a variety of translation-based activities aimed at developing students’ inter-linguistic and intercultural competences, we have compiled an aligned parallel corpus of study with ten contemporary Brazilian novels and their ...
Diva Cardoso De Camargo
doaj   +1 more source

Mechanically Triggered DNA Nanovehicles for Targeted Dual‐Drug Cancer Therapy

open access: yesAdvanced Science, EarlyView.
A mechanically triggered DNA nanovehicle is introduced that co‐releases two anticancer drugs in response to integrin‐mediated cellular forces. Cholesterol‐anchored DNA assemblies undergo force‐induced unfolding at cell–cell junctions, enabling selective, localized dual‐drug activation in cancer cells while minimizing off‐target toxicity in low‐tension ...
Murali Mohana Rao Singuru   +2 more
wiley   +1 more source

From English to Indonesian: A Study of Student Approaches to Translation across Different Source Languages

open access: yesUtamax
This study investigates the translation practices of English Literature students, focusing on their application of theoretical frameworks in translating texts from English and Indonesian. While translation theory is typically taught in academic settings,
Ana Rosida, Herdi Herdi
doaj   +1 more source

A Labour Useful to Students: Contrasting Perspectives on Teaching Translation Studies

open access: yesCelt: A Journal of Culture, English Language Teaching & Literature, 2018
Translation Pedagogy is one of the most under-developed fields of Translation Studies. This paper will provide an introduction to three different approaches to the teaching of Translation: the Classical European, the “transmissionist” approach and the ...
Harry Aveling
doaj   +1 more source

Ethical and Frugal Approaches to Animal Experimentation in Bioelectronics and Neural Engineering—An Invertebrate Renaissance?

open access: yesAdvanced Electronic Materials, EarlyView.
Invertebrates are the classic neuroscience models and should make a comeback. Invertebrate organisms can be a more ethical and cost‐effective way to move bioelectronics research forward more rapidly. ABSTRACT The accelerating development of bioelectronic neural interfaces has brought increased attention to ethical considerations surrounding in vivo ...
Eric Daniel Głowacki
wiley   +1 more source

Enhancing translation teaching for L2 learners through ChatGPT: A study of AI-assisted Arabic-German translation

open access: yesEast European Journal of Psycholinguistics
This study investigates the effectiveness of using ChatGPT as a teaching tool in enhancing Arabic-to-German translation skills. An experimental group, using ChatGPT throughout a 15-week semester, was compared to a control group that followed traditional ...
Nadia Naqrash   +3 more
doaj   +1 more source

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