Results 121 to 130 of about 90,174 (301)
Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma
Molecular Oncology, EarlyView.Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski +10 more
wiley +1 more source
The construction of translation planes from projective spaces
, 1964 Can every (nonDesarguesian) projective plane be imbedded (in some natural, geometric fashion) in a (Desarguesian) projective space? The question is new but important, for, if the answer is yes, two entirely separate fields of research can be united. This
Bruck, R.H, Bose, R.C
core +1 more source
Journal of Industrial Design and Engineering Graphics, 2006 This paper presents the major contribution of geometrical transformations in the structure and organization of the shapes which compose industrial products. Geometrical transformations, such as symmetry, translation, rotation, homology etc.
MARIN Dumitru
doaj
Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis
Molecular Oncology, EarlyView.This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht +3 more
wiley +1 more source
Weakening the nuclear envelope: Lamin B receptor in melanoma metastasis
Molecular Oncology, EarlyView.LBR‐driven nuclear fragility supports melanoma invasion. A: Melanocyte presents low LBR (Lamin B Receptor) levels, maintaining nuclear integrity and lamina‐chromatin tethering. B: During malignant progression, upregulation of LBR clusters at the INM (Inner Nuclear Membrane) during confined migration causes local lamina weakening and cholesterol ...
Francesca Lorenzini +1 more
wiley +1 more source
Mystical translation in Patrick White's Voss
, 2014 Patrick White’s Voss consorts with the divine. Its hallucinatory prose transforms the desert interior of the Australian continent into a numinous landscape where even “the souls of rocks” are worthy of consideration (204).
Conti, Chris (R16777)
core
, 1997 The unitals in the Hall plane are studied by deriving PG(2, q2) and observing the effect on the unitals of PG(2, q2). The number of Buekenhout and Buekenhout-Metz unitals in the Hall plane is determined.
Barwick, S.
core +1 more source
Molecular Oncology, EarlyView.Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim +3 more
wiley +1 more source
Molecular Oncology, EarlyView.The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington +10 more
wiley +1 more source
Majallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Bābul, 2008 BACKGROUND AND OBJECTIVE: Different ideas have proposed for translation and rotation values of lumbar vertebrae in sagittal plane that is a challenge for physicians. Calculating method can be one of the difference sources.
MT Taghipour Darzi, +5 more
doaj