Results 71 to 80 of about 86,943 (261)
Translophagy—A potential link between autophagy impairment and translational errors
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source
Ethyl 2-(4-bromophenyl)-1-sec-butyl-1H-benzimidazole-5-carboxylate
In the title compound, C20H21BrN2O2, the bromophenyl ring is twisted by 40.13 (8)° from the benzimidazole mean plane and the Br atom deviates by 0.753 (1) Å from that plane.
Natarajan Arumugam +3 more
doaj +1 more source
Transposed translation planes [PDF]
A detailed study of the transposed translation planes which are also given by dual spreads is made using the matrix representation of translation planes.
openaire +2 more sources
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Introduction In this paper, we intend to show that without any certain growth condition on the weight function, we always able to present a weighted sup-norm on the upper half plane in terms of weighted sup-norm on the unit disc and supremum of ...
ma ardalani
doaj
3-(1-Phenylethyl)-1,3-thiazinane-2-thione
In the title molecule, C12H15NS2, the 1,3-thiazinane ring has a half-boat conformation; the C atom at position 5 deviates by 0.715 (2) Å from the mean plane (P) of the remaining five atoms.
Chong-jia Liang, Fu-feng Yan
doaj +1 more source
On Transposed Translation Planes
This paper is devoted to the study of a translation plane π(C) associated with a t-spread set C and its transposed t-spread set C t. In this paper, an explicit matrix form of the inverse of an isomorphism from a translation plane into another translation plane associated with t-spread sets is derived and proved that two translation planes associated ...
K. Satyanarayana +1 more
openaire +2 more sources
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
The geometry of GL(2,q) in translation planes of even order q2
In this article we show the following: Let π be a translation plane of even order q2 that admits GL(2,q) as a collineation group. Then π is either Desarguesian, Hall or Ott-Schaeffer.
N. L. Johnson
doaj +1 more source
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source

