Results 91 to 100 of about 90,174 (301)

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

3-(1-Phenylethyl)-1,3-thiazinane-2-thione

open access: yesActa Crystallographica Section E, 2009
In the title molecule, C12H15NS2, the 1,3-thiazinane ring has a half-boat conformation; the C atom at position 5 deviates by 0.715 (2) Å from the mean plane (P) of the remaining five atoms.
Chong-jia Liang, Fu-feng Yan
doaj   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Wallpaper Groups: The Discontinuous Groups of Rotation and Translation in the Plane

open access: yes, 2000
An undergraduate tutorial on wallpaper groups, with illustrations of the 17 wallpapers groups and a wallpaper gallery. Technically, the derivation of all discontinuous groups of rotation and translation in the plane.
Lee, Xah
core  

Two Equivalent Presentations for the Norm of Weighted Spaces of Holomorphic Functions on the Upper Half-plane

open access: yesپژوهش‌های ریاضی, 2019
Introduction In this paper, we intend to show that without any certain growth condition on the weight function, we always able to present a weighted sup-norm on the upper half plane in terms of weighted sup-norm on the unit disc and supremum of ...
ma ardalani
doaj  

Ethyl 2-(4-bromophenyl)-1-sec-butyl-1H-benzimidazole-5-carboxylate

open access: yesActa Crystallographica Section E, 2011
In the title compound, C20H21BrN2O2, the bromophenyl ring is twisted by 40.13 (8)° from the benzimidazole mean plane and the Br atom deviates by 0.753 (1) Å from that plane.
Natarajan Arumugam   +3 more
doaj   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

The decay of cyclonic eddies by Rossby wave radiation

open access: yes, 1998
It is argued that because shallow water cyclones on a β-plane drift westward at a speed equal to an available Rossby wave phase speed, they must radiate energy and cannot, therefore, be steady. The form of the Rossby wave wake accompanying a quasi-steady
McDonald, NR
core  

The geometry of GL(2,q) in translation planes of even order q2

open access: yesInternational Journal of Mathematics and Mathematical Sciences, 1978
In this article we show the following: Let π be a translation plane of even order q2 that admits GL(2,q) as a collineation group. Then π is either Desarguesian, Hall or Ott-Schaeffer.
N. L. Johnson
doaj   +1 more source

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

open access: yesMolecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann   +61 more
wiley   +1 more source

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