Results 121 to 130 of about 30,282 (293)
Molecular Oncology, EarlyView.Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach +9 more
wiley +1 more source
Molecular Oncology, EarlyView.LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang +9 more
wiley +1 more source
Translation Planes of Dimension Two with Odd Characteristic
, 1980 A translation plane of dimension d over its kernel K = GF(q) can be represented by a vector space of dimension 2d over K. The lines through the zero vector form a “spread”; i.e., a class of mutually independent vector spaces of dimension d which cover ...
T. G. Ostrom
core +1 more source
Translating whole‐genome doubling into precision medicine in cancer
Molecular Oncology, EarlyView.Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley +1 more source
Symplectic translation planes of even order
, 2006 Symplectic translation planes of even order are investigated. Such planes are characterised by the existence of completely regular line--ovals, and these line--ovals give rise to symmetric designs isomorphic to certain designs investigated by Kantor. The
MASCHIETTI, Antonio
core
, 2006 Publicación ISIIt is shown that for every semifield spread in PG(3, q) and for every parabolic Buekenhout-Metz unital, there is a collineation group of the associated translation plane that acts transitively and regularly on the affine points of the ...
Johnson, Norman L. +4 more
core +1 more source
Molecular Oncology, EarlyView.Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley +1 more source
FEBS Open Bio, EarlyView.RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz +6 more
wiley +1 more source
Spreads and unitals in topological translation planes
, 2005 Bu çalışmada, topolojik öteleme düzlemlerinde yayılımlar ve birimlikler incelenmiştir. Birinci bölümde giriş, ikinci bölümde gerekli olan temel kavramlar verilmiştir.
Demirel, Oğuzhan
core
FEBS Open Bio, EarlyView.This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel +4 more
wiley +1 more source