Results 51 to 60 of about 28,389 (247)

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

FEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva, Puspa Kunwar, Md Ibnul Rifat Rahman, Joanna Koryo Kwao, Nathan Lehman, Zihan Zhang, Trenton Paul, Claire Cheng, Nicholas Truex, Hui‐Ting Lee, Jun Zhang   +10 more
wiley   +1 more source

STYLISTIC MEANS OF IMPLEMENTING THE IDEA OF THE WORLD’S IRIDESCENCE IN PH.K. DICK’S “UBIK” IN THE CONTEXT OF TRANSLATION TRANSFORMATIONS [PDF]

Alfred Nobel University Journal of Philology
The article deals with the formation means of the idea of the world’s iridescence or illusiveness, its stylistic and translation aspects within the textual framework of Ph.K. Dick’s novel “Ubik” and its translat- ed version in Ukrainian. The relevance
Svitlana F. Aleksenko, Larysa I. Taranenko   +1 more
doaj   +1 more source

Global Registration of Terrestrial Laser Scanner Point Clouds Using Plane-to-Plane Correspondences

Remote Sensing, 2020
Registration of point clouds is a central problem in many mapping and monitoring applications, such as outdoor and indoor mapping, high-speed railway track inspection, heritage documentation, building information modeling, and others.
Nadisson Luis Pavan, Daniel Rodrigues dos Santos, Kourosh Khoshelham   +2 more
doaj   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

2-{4-[(1,3-Benzodioxol-5-yl)methyl]piperazin-1-yl}pyrimidine

Acta Crystallographica Section E, 2013
In the title compound, C16H18N4O2, known also as peribedil, the dihedral angle between the mean planes of the pyrimidine and benzene rings is 56.5 (8)°. The 1,3-dioxole fragment adopts an envelope conformation with the methylene C atom forming
Chunli Wu, Jieming Li, Huijie Wei, Ye Hang, Yueming Jiang   +4 more
doaj   +1 more source

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

Molecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts, Senada Koljenović, Elise Daems, Karolien De Wael, Marc Peeters, Léon C. van Kempen, Greetje Vanhoutte, Karen Zwaenepoel, Timon Vandamme   +8 more
wiley   +1 more source

Femoral Translation in Patients with Unicompartmental Osteoarthritis—A Cohort Study

Biomechanics
The use of three-dimensional (3D) gait analysis to image femorotibial translation can aid in the diagnosis of pathology and provide additional insight into the severity of KOA (knee osteoarthritis). Femorotibial translation is of particular importance in
Mathis Wegner, Simon Kuwert, Stefan Kratzenstein, Maciej J. K. Simon, Babak Moradi   +4 more
doaj   +1 more source

Adenosine‐to‐inosine editing of miR‐200b‐3p is associated with the progression of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira, Anna Skwarska, Karolina Chwialkowska, Agnieszka Ostrowska, Gabriela Sokolowska, Anna Zeller, Anna Erol, Andrzej Eljaszewicz, Bartosz Hanczaruk, Anna Michalska‐Falkowska, Agnieszka Tarasik, Joanna Reszec‐Gielazyn, Pawel Knapp, Marcin Moniuszko, Adam Kretowski   +14 more
wiley   +1 more source

Di-tert-butyldiisothiocyanatotin(IV)

IUCrData
The title compound, [Sn(C4H9)2(NCS)2], which crystallizes with one and a half molecules in the asymmetric unit, represents a new structure type for intermolecular sulfur...tin interactions, which is characterized by an antiparallel (A) arrangement of the
Anne Kamrowski, Hans Reuter
doaj   +1 more source

Laminectomy without instrumentation for surgical treatment of metastatic spinal cord compression

Coluna/Columna, 2014
OBJECTIVE: To analyze the development of mechanical complications as a result of spinal decompression or cauda equina in patients with metastatic tumors of the spine via laminectomy or laminoartrectomy without fixation.
Paulo Alvim Borges, William Gemio Jacobsen Teixeira, Douglas Kenji Narazaki, Alexandre Fogaça Cristante, Cesar Salge Ghilardi, Manoel Jacobsen Teixeira, Olavo Pires de Camargo, Tarcisio Eloy Pessoa de Barros Filho   +7 more
doaj   +1 more source