Results 121 to 130 of about 7,997,205 (248)

Unraveling the epigenetic code in cancer cell–tumor microenvironment crosstalk

Molecular Oncology, EarlyView.
Epigenetic regulation is a key driver of cancer development and progression. Diverse epigenetic alterations in cancer cells and components of the tumor microenvironment (TME) orchestrate their communication through multiple mechanisms. We discuss how the epigenetic code coordinates bidirectional cancer cell–TME crosstalk to promote cancer progression ...
Ji Hoon Park, Mi‐Young Kim
wiley   +1 more source

Evaluating accuracy and fluency in machine and human translation: a genre-based multidimensional quality metrics (MQM) study in an English as a foreign language (EFL) context

Cogent Arts & Humanities
Despite the growing use of Machine Translation (MT) in translation practice, limited studies have examined genre-based quality comparison between machine and Human Translation (HT) using Multidimensional Quality Metrics (MQM) framework, with limited ...
Esti Junining, Siti Zaidah Zainuddin
doaj   +1 more source

Arginine methylation as a regulatory ratchet in cancer: From substrate selection to malignant‐state stabilization

Molecular Oncology, EarlyView.
Arginine methylation can be viewed as a persistence‐prone post‐translational modification regulated by a network of PRMTs. Competitive and compensatory interactions among PRMTs can redistribute methylation across substrate pools shaped by sequence, structural, spatial, and environmental layers, reinforcing RNA‐processing, chromatin, and signaling ...
So Hyun Kwon, Ji Min Lee
wiley   +1 more source

A comparative evaluation of ChatGPT and human translation of Sundanese cultural terms

Studies in English Language and Education
This study addresses a gap in low-resource language translation research by comparing how ChatGPT and a human translator render Sundanese cultural terms into English and evaluating both outputs using established translation quality dimensions.
Ina Sukaesih, Fanny Puji Rakhmi, Farizka Humolungo, Septina Indrayani, Taufik Eryadi Abdillah   +4 more
doaj   +1 more source

Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer

Molecular Oncology, EarlyView.
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim, Maryam Aslam, Elouise Torruella, Alphons Sony, Asif Rahman, Simira Smith, Columba de la Parra, Moira Sauane   +7 more
wiley   +1 more source

Unreferenced English articles' translation quality-oriented automatic evaluation technology using sparse autoencoder under the background of deep learning.

PLoS One, 2022
Li H, Deng J.
europepmc   +1 more source

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

Molecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic, Rafael Stroggilos, Mladen Marinkovic, Ana Djuric, Suzana Stojanovic‐Rundic, Radmila Jankovic, Sergi Castellvi‐Bel, Remond J.A. Fijneman, Antonia Vlahou, Jerome Zoidakis, Milena Cavic   +10 more
wiley   +1 more source

Adapting machine translation education to the neural era : a case study of MT quality assessment

, 2023
The use of automatic evaluation metrics to is well established in the translation industry. Whereas it is relatively easy to cover the word- and character-based metrics in an MT course, it is less obvious to integrate the newer neural metrics.
Vanroy, BramUGent0001615296528020026585439747705382060000-0002-4622-8364C50B0474-7EE0-11E7-B38D-2BA4AD28A064, Popovic, Majaeditor, Brenner, Juditheditor, Nurminen, Maryeditor, Mikhailov, Mikhaileditor, Forcada, Mikeleditor, Alvarez Vidal, Sergieditor, Scarton, Carolinaeditor, Ranasinghe, Tharindueditor, Koponen, Maariteditor, Aranberri, Noraeditor, Parra Escartín, Carlaeditor, Latomaa, Sirkkueditor, Nunziatini, Maraeditor, Tezcan, ArdaLW220020058519838020017673550000-0002-8707-6176E4E9C51C-9502-11E3-A4F6-4F4B11BDE39D, Macken, LieveLW228020002457680000-0001-7516-7487F93DB0F6-F0ED-11E1-A9DE-61C894A0A6B4, Vanmassenhove, Evaeditor, Schierl, Frederikeeditor, Moniz, Helenaeditor   +18 more
core  

The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer

Molecular Oncology, EarlyView.
Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad, Silvio Carlo Ermanno Tosatto, Emanuela Leonardi   +2 more
wiley   +1 more source

Gut microbiota alterations in patients with non‐small‐cell lung cancer undergoing chemoradiotherapy

Molecular Oncology, EarlyView.
We investigated the impact of concurrent chemoradiotherapy (CRT) on the gut microbiota in patients with locally advanced non‐small‐cell lung cancer. Overall gut microbiota composition remained largely stable throughout CRT while antibiotic exposure may influence microbial diversity.
Hanne Marte Nymoen, Zhi Zhao, Henrik Horndalsveen, Maria Moksnes Bjaanæs, Bjørn Henning Grønberg, Tarje Halvorsen, Tesfaye Madebo, Marianne Aanerud, Jussi Koivunen, Kersti Oselin, Saulius Cicenas, Nina Helbekkmo, Jarkko Ahvonen, Maria Silvoniemi, Tine Norman Alver, Tonje Dalen, Åsa Kristina Öjlert, Saima Jamil Farooqi, Åslaug Helland, Vilde Drageset Haakensen   +19 more
wiley   +1 more source