Results 111 to 120 of about 1,664,763 (284)

Quality Aspects In Institutional Translation

open access: yes, 2017
The purpose of this volume is to explore key issues, approaches and challenges to quality in institutional translation by confronting academics’ and practitioners’ perspectives. What the reader will find in this book is an interplay of two approaches: academic contributions providing the conceptual and theoretical background for discussing quality on ...
Svoboda, Tomáš   +2 more
openaire   +3 more sources

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

open access: yesMolecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni   +11 more
wiley   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau   +8 more
wiley   +1 more source

Translation Quality Assessment

open access: yesMutatis Mutandis, 2009
The relevance of, and justification for, translation quality assessment (TQA) is stronger than ever: professional translators, their clients, translatological researchers and trainee translators all rely on TQA for different reasons. Yet whereas there is general agreement about the need for a translation to be "good," "satisfactory" or "acceptable ...
openaire   +1 more source

NKCC1: A key regulator of glioblastoma progression

open access: yesMolecular Oncology, EarlyView.
Glioblastoma (GBM) progression is driven by disrupted chloride cotransporter homeostasis. NKCC1 is highly expressed in stem‐like, astrocytic, and progenitor cells, correlating with earlier recurrence, while overall survival remains unaffected. NKCC1 serves as a prognostic marker and potential therapeutic target, linking chloride transporter imbalance ...
Anja Thomsen   +5 more
wiley   +1 more source

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

open access: yesMolecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak   +10 more
wiley   +1 more source

Quality Expectations of Machine Translation [PDF]

open access: yes, 2018
Machine Translation (MT) is being deployed for a range of use-cases by millions of people on a daily basis. There should, therefore, be no doubt as to the utility of MT. However, not everyone is convinced that MT can be useful, especially as a productivity enhancer for human translators.
openaire   +3 more sources

Molecular cancer prevention: Intercepting disease

open access: yesMolecular Oncology, EarlyView.
Oncological practice must evolve, from treating established tumours to proactive cancer interception before clinical manifestation. This will require mechanistic insight into tumour initiation, validated biomarkers of early disease development and redesigned clinical trials, enabling cancer interception to become a core pillar of oncology with the ...
Charlotte Grieco   +2 more
wiley   +1 more source

Readability, Fluency and Error identification when using Machine Translation and AI to translate medical research texts

open access: yesLangue(s) & Parole
With the improvements in the algorithms used to develop online machine translation tools and the growing relevance of AI there is a raising concern related to the quality of these tools’ outputs.
Raquel Moreira
doaj   +1 more source

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