Results 91 to 100 of about 7,997,205 (248)

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

TransBooster: boosting the performance of wide-coverage machine translation systems [PDF]

, 2005
We propose the design, implementation and evaluation of a novel and modular approach to boost the translation performance of existing, wide-coverage, freely available machine translation systems based on reliable and fast automatic decomposition of the ...
Mellebeek, Bart, Way, Andy, Khasin, Anna, van Genabith, Josef   +3 more
core   +2 more sources

Translation technology explored: Has a three-year maturation period done Google Translate any good?

Stellenbosch Papers in Linguistics Plus, 2014
Language users in multilingual environments who are trying to make sense of the linguistic challenges they face may well regard the advent of online machine translation (MT) applications as a welcome intervention.
Lotz, Susan, van Rensburg, Alta
doaj   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

The ethical dimension of translation revision : an empirical study [PDF]

, 2007
This paper investigates translation revision using think-aloud protocols. Ten professional translators were asked to think aloud while revising three draft translations.
Künzli, Alexander
core   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

Learner vs. professional translations into Russian: Lexical profiles

Translation and Interpreting : the International Journal of Translation and Interpreting Research, 2018
One of the relatively recent trends in learner corpora research is building and exploiting learner translator corpora. Within corpus-based translation studies (CTS) translations are approached as a special variety of the target language. They are usually
Maria Kunilovskaya, Natalia Morgoun, Alexey Pariy   +2 more
doaj   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source

Efektivitas Penggunaan Kamus Digital Almaany dalam Meningkatkan Kualitas Terjemahan Teks Bahasa Arab

Uktub
Translating Arabic texts is a fundamental skill that must be mastered by students of Arabic, as it involves accurate vocabulary comprehension, deep contextual understanding, and appropriate transfer of meaning from the source language to the target ...
Achmad Affandy
doaj   +1 more source