Results 131 to 140 of about 2,227,389 (303)

Translation of Sounds for Children: an Example of a Multimodal Work

open access: yes, 2023
Translation of poetry, particularly intended for children, has always been considered as one of the most problematic and challenging sub-fields of literary translation.
Hastürkoğlu, Gökçen   +1 more
core  

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim   +17 more
wiley   +1 more source

Abraham Sybant Tames the taming of the shrew for the Amsterdam stage (1654) Abraham Sybant Tames the taming of the shrew for the Amsterdam stage (1654)

open access: yesIlha do Desterro, 2008
In recent years, translation studies have found themselves in a veritable flux. After decades of concentration on the purely linguistic correspondences between the so-called source text and the actual translation in the target language (an approach of ...
Ton Hoenselaars   +1 more
doaj  

Engineering IL‐4 resistant proinflammatory human myeloid cells for cancer immunotherapy

open access: yesMolecular Oncology, EarlyView.
We developed a scalable workflow to generate proinflammatory human myeloid cells. CRISPR/Cas9‐edited CD34+ hematopoietic stem and progenitor cells were expanded and differentiated with M‐CSF. Deletion of STAT6 or STAT6/NFKB1 enhanced macrophage proinflammatory gene expression and cytokine secretion in the presence of IL‐4 while maintaining antibody ...
Theresa Barberi, Alan D. Friedman
wiley   +1 more source

Unpaired image translation to mitigate domain shift in liquid argon time projection chamber detector responses

open access: yesMachine Learning: Science and Technology
Deep learning algorithms often are developed and trained on a training dataset and deployed on test datasets. Any systematic difference between the training and a test dataset may severely degrade the final algorithm performance on the test dataset—what ...
Yi Huang   +6 more
doaj   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

open access: yesFEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz   +6 more
wiley   +1 more source

Interpretation and translation in Guy Delisle’s Shenzhen [PDF]

open access: yes, 2012
As a piece of travel writing describing Guy Delisle’s trip to China as an animator, Shenzhen: A Travelogue from China (2006) is readable in relation to translation as a practice and as a metaphor.
Evans, Jonathan
core  

Comparing rule-based and data-driven approaches to Spanish-to-Basque machine translation [PDF]

open access: yes, 2007
In this paper, we compare the rule-based and data-driven approaches in the context of Spanish-to-Basque Machine Translation. The rule-based system we consider has been developed specifically for Spanish-to-Basque machine translation, and is tuned to ...
Stroppa, Nicolas   +3 more
core   +2 more sources

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

open access: yesFEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová   +2 more
wiley   +1 more source

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

open access: yesFEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya   +2 more
wiley   +1 more source

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