Results 141 to 150 of about 2,227,389 (303)
Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells
FEBS Open Bio, EarlyView.Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim +4 more
wiley +1 more source
Paradigm Shifts for Literary Translation
Translation Studies: Theory and PracticeMy essay argues that there have been important paradigm shifts for the translation of Arabic literature to English during the last century from Orientalist to Civilization Studies and to Modeling, for example.
openaire +2 more sources
Frontiers in EducationIntroductionThe rapid development of large language models, particularly ChatGPT, has generated growing interest in their potential applications in translation studies. Despite the increasing number of publications on this topic, a comprehensive overview
Sukayna Ali, Marwan Jarrah
doaj +1 more source
FEBS Open Bio, EarlyView.The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley +1 more source
, 2014 1 box, contains 5 books and 3 folded cards. Each artist created a small book of identical dimensions to reflect her interpretation of the word SHIFT . Edition limited to 20 copies, numbered and signed by artists.
Collections, Special +2 more
core
Inflated expectations: the strange craze for translational research on aging
EMBO ReportsThe geroscience research program of the last decade has entailed a shift of focus in research on aging, away from understanding its underlying biology and towards translation into anti-aging treatments—a shift that is premature.
David Gems, Simon Okholm, Maёl Lemoine
doaj +1 more source
Yeast Gcn2 retains activity following humanization of its auto‐phosphorylation region
FEBS Open Bio, EarlyView.Using Saccharomyces cerevisiae as a model to study Gcn2 activation and regulation is limited by the lack of antibodies detecting phosphorylated Gcn2. To overcome this, we engineered Gcn2‐HsC, a yeast Gcn2 variant recognizable by commercial anti‐human phospho‐GCN2 antibodies.
Reuben A. Anderson +2 more
wiley +1 more source
An Investigation into Automatic Translation of Prepositions in IT Technical Documentation from English to Chinese [PDF]
, 2010 Machine Translation (MT) technology has been widely used in the localisation industry to boost the productivity of professional translators. However, due to the high quality of translation expected, the translation performance of an MT system in ...
Sun, Yanli
core +1 more source
Ionomycin suppresses cancer cell growth by disrupting mitochondrial transcription
FEBS Open Bio, EarlyView.In this study, we identify a new function for the selective Ca2+ ionophore, ionomycin, as an inhibitor of mitochondrial transcription. Both total and nascent RNA analyses revealed that ionomycin treatment reduces the transcription of mitochondrial genes.
Lishen Wang +10 more
wiley +1 more source
FEBS Open Bio, EarlyView.Lactoferrin promotes wound healing by activating MAPK, PI3K/Akt, and extracellular matrix pathways, enhancing fibroblast remodeling, proliferation, and re‐epithelialization. These mechanisms highlight its therapeutic potential in inflammation control, tissue repair, and remodeling.
Morgana Lüdtke Azevedo +4 more
wiley +1 more source