Results 111 to 120 of about 526,930 (298)
Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer
Molecular Oncology, EarlyView.Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni +11 more
wiley +1 more source
Molecular Oncology, EarlyView.Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau +8 more
wiley +1 more source
On Optional Shifts in Translation from Persian into English
Vertimo Studijos, 2019 Some changes always take place in the process of transferring the meaning embedded in the source text into the target text. The present paper aims at investigating the formal dissimilarities between the source and target texts through the examination of ...
Helia Vaezian, Fatemeh Ghaderi Bafti
doaj +1 more source
Paradigm shift required for translational research on the brain [PDF]
Experimental & Molecular MedicineAbstractBiomedical research on the brain has led to many discoveries and developments, such as understanding human consciousness and the mind and overcoming brain diseases. However, historical biomedical research on the brain has unique characteristics that differ from those of conventional biomedical research.
Jong Hyuk Yoon +9 more
openaire +4 more sources
Molecular Oncology, EarlyView.CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak +10 more
wiley +1 more source
Translation Studies: Theory and PracticeThe paper examines eco-translatology in the context of film translation from English into Ukrainian. Its primary aim is to apply an eco-translational approach to audiovisual translation and to identify the linguistic, cultural and communicative shifts ...
Artur Gudmanian, Andriana Ivanova
doaj +1 more source
David Bellos’ Indirect Translation of Ismail Kadare’s The File on H: A Contextual Analysis
International Journal of Literary Linguistics, 2016 This article is a linguistic study of David Bellos’ indirect translation of Ismail Kadare’s The File on H (1997), a novel first published in 1980-1981 in the Albanian literary review Nëntori, and translated into English on the basis of Jusuf Vrioni’s ...
Silvia Kadiu
doaj +1 more source
Fundamental Limits in Multi-image Alignment
, 2016 The performance of multi-image alignment, bringing different images into one coordinate system, is critical in many applications with varied signal-to-noise ratio (SNR) conditions.
Aguerrebere, Cecilia +3 more
core +1 more source
Molecular cancer prevention: Intercepting disease
Molecular Oncology, EarlyView.Oncological practice must evolve, from treating established tumours to proactive cancer interception before clinical manifestation. This will require mechanistic insight into tumour initiation, validated biomarkers of early disease development and redesigned clinical trials, enabling cancer interception to become a core pillar of oncology with the ...
Charlotte Grieco +2 more
wiley +1 more source
Translation shifts of pronoun in the novel Twilight
Journal of Applied Studies in Language, 2019 Translation could be defined as converting one language (Source Language) to another language (Target Language) so that the target language could convey the intended message in the source language.
Made Verayanti Utami +1 more
doaj +1 more source