Results 111 to 120 of about 1,336,089 (294)

Knowledge translation strategies to support the sustainability of evidence-based interventions in healthcare: a scoping review. [PDF]

open access: yesImplement Sci, 2023
Flynn R   +7 more
europepmc   +1 more source

Micro-strategies of Contextualization Cross-national Transfer of Socially Responsible Investment [PDF]

open access: yes
This paper examines how individuals select and mobilize local institutions when they transfer business practices across societies that are construed as dissimilar to one another.
Eva Boxenbaum, Jean-Pascal Gond
core  

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Enhancing scarce-resource language translation through pivot combinations [PDF]

open access: yes, 2011
Chinese and Spanish are the most spoken languages in the world. However, there is not much research done in machine translation for this language pair. We experiment with the parallel Chinese-Spanish corpus (United Nations) to explore alternatives of SMT
Banchs, Rafael E.   +2 more
core  

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

La función de la teoría de la traducción en el desarrollo de las prácticas traductivas

open access: yesPhilologia Romanistica Cultura
The aim of the article is to specify the role of translation theory in the field of the translation process. Within the principles of translation, all phases of translation are analysed, as well as the need to understand the source text from a ...
Sofia Tileschová
doaj   +1 more source

O Auto da Compadecida - A Dog's Will: an analysis of the translation of idioms in the English subtitle [PDF]

open access: yes, 2014
TCC (Graduação) - Universidade Federal de Santa Catarina. Centro de Comunicação e Expressão. Letras Inglês.The objective of this study is to analyse the English subtitles of the Brazilian film O Auto da Compadecida – A Dog’s Will (Arraes, 2000) – in ...
Lubianco de Sá, Emilene
core  

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

open access: yesMolecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni   +11 more
wiley   +1 more source

Machine Translation of Low-Resource Spoken Dialects: Strategies for Normalizing Swiss German

open access: yes, 2018
The goal of this work is to design a machine translation (MT) system for a low-resource family of dialects, collectively known as Swiss German, which are widely spoken in Switzerland but seldom written.
Baeriswyl, Michael   +3 more
core  

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau   +8 more
wiley   +1 more source

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