Results 61 to 70 of about 419,375 (265)
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Mechanisms of IgE‐mediated food allergy and the role of allergen‐specific B cells
FEBS Letters, EarlyView.Food allergy arises when allergen‐specific B cells preferentially produce immunoglobulin E (IgE) antibodies against harmless foods. This article explains the mechanisms driving IgE‐mediated reactions, highlights the central role of these B cells, and discusses how natural tolerance (NT) and oral immunotherapy (OIT) can reshape allergic immune responses.
Juan‐Felipe López +2 more
wiley +1 more source
The Strategies and Problems in Film Title Translation
Respectus Philologicus, 2016 The translation of fictional work is not simply a substitution of source language characters with the target language signs, but rather a complex phenomenon, related to many social, cultural and communication components, rendering the transformation of ...
Robertas Kudirka +2 more
doaj +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
HumanitiesTo completely understand Dante’s work, we would need to perfectly comprehend the foundations on which it is built, as well as Dante’s own “constructs” and reinterpretations of earlier texts—the transformations of these texts and the whole ideological ...
Monika Šavelová
doaj +1 more source
Translating Korean Nature. Translation Strategies in Lithuanian and English Literary Translation
Research in Language, 2020 World literatures today often impose a separation of narratives from their geographic and linguistic origins. Translated versions of literary texts that were created and received within local cultural contexts, when translated, enter new, foreign contexts.
openaire +5 more sources
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Konsertoversettelse av kunstsanger – musikk- og/eller tekststyrt?
Studia Musicologica NorvegicaAnalyser av oversettelser av kunstsanger til fremføringsformål er et relativt nytt kapittel i oversettelsesvitenskapen. Med utgangspunkt i oversettelsene av Griegs norske sanger til tysk og hans tyske sanger til norsk gis i dette arbeidet først en ...
Sigmund Kvam
doaj +1 more source