Results 81 to 90 of about 4,480,419 (303)

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

FEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg, Martine Hjeltnes, Josephine Krieger, Joshua E. Elias, Maria Stensland, Kristian Holm, Xiaojun Jiang, Chuki Khangsar, Tuula A. Nyman, Arthur Kaser, Johannes R. Hov, Tom H. Karlsen, Nicole C. Kaneider, Frode L. Jahnsen, Georg Schneditz   +14 more
wiley   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Improving the post-editing experience using translation recommendation: a user study [PDF]

, 2010
We report findings from a user study with professional post-editors using a translation recommendation framework (He et al., 2010) to integrate Statistical Machine Translation (SMT) output with Translation Memory (TM) systems.
He, Yifan, Way, Andy, Roturier, Johann, van Genabith, Josef, Ma, Yanjun   +4 more
core   +2 more sources

Are ideophones translatable? The case of translating isiZulu ideophones in DBZ Ntuli’s short story Uthingo Lwenkosazana (The Rainbow)

Literator, 2018
The meaning of words comes into play when words as units of translation are to be translated from one language into another. Lexical items that are extant in one language but not in others pose enormous problems for translators.
Mthikazi Rose Masubelele
doaj   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Towards a user-friendly webservice architecture for statistical machine translation in the PANACEA project [PDF]

, 2011
This paper presents a webservice architecture for Statistical Machine Translation aimed at non-technical users. A workflow editor allows a user to combine different webservices using a graphical user interface.
Poch, Marc, Toral, Antonio, Way, Andy, Pecina, Pavel   +3 more
core   +1 more source

Experiments on domain adaptation for patent machine translation in the PLuTO project [PDF]

, 2011
The PLUTO1 project (Patent Language Translations Online) aims to provide a rapid solution for the online retrieval and translation of patent documents through the integration of a number of existing state-of-the-art components provided by the project ...
Tinsley, John, Zhang, Jian, Way, Andy, Ceausu, Alexandru   +3 more
core   +2 more sources

Epigenetic reprogramming of lineage switching in cancer

FEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı, Burcu Akman, Ezgi Bağırsakçı, Nese Atabey, Serap Erkek‐Ozhan   +4 more
wiley   +1 more source

Contextualized translation: An alternative strategy to translate culture-specific Moroccan Arabic Proverbs in English [PDF]

This article aims to shed light upon the difficulty that arises when translating culture-specific proverbial utterances from a source language (SL) to a target language (TL).
Abrighach, Rajae
core   +1 more source

Reproductive and Adaptive Strategies in Translating Comparative Units (on the Material of the Italian, English and Ukrainian Languages)

Вісник Харківського національного університету імені В. Н. Каразіна. Серія Іноземна філологія. Методика викладання іноземних мов
The article deals with the problem of rendering comparative units of the Italian language into English and Ukrainian through the lens of the translation strategies of domestication and foreignization.
Iryna Skrypnik
doaj   +1 more source