Results 91 to 100 of about 4,480,419 (303)

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

open access: yesFEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee   +2 more
wiley   +1 more source

Amatorskie tłumaczenie online

open access: yesMiędzy Oryginałem a Przekładem
AMATEUR ONLINE TRANSLATION: FANFICTION TRANSLATION (BASED ON A SAMPLE OF POLISH TRANSLATIONS FROM ENGLISH PUBLISHED ON THE AO3 PLATFORM) Translating fanfiction is a notably understudied phenomenon that plays a significant role in fan communities ...
Dorota Pudo
doaj   +1 more source

Human versus AI in Literary Translation: Rendition of Cultural Nuances in Shahnameh [PDF]

open access: yesMedia and Intercultural Communication: A Multidisciplinary Journal
This comparative case study aims to provide a descriptive account of the types and frequencies of culture-specific items (CSIs) based on Newmark’s (1988) five areas of CSIs and to specify the translation strategies used by human translators and an ...
Aysa Arjmandpour, Hossein Bahri
doaj   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

open access: yesFEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri   +5 more
wiley   +1 more source

Combining semantic and syntactic generalization in example-based machine translation [PDF]

open access: yes, 2011
In this paper, we report our experiments in combining two EBMT systems that rely on generalized templates, Marclator and CMU-EBMT, on an English–German translation task. Our goal was to see whether a statistically significant improvement could be achieved
Way, Andy   +3 more
core   +2 more sources

Translophagy—A potential link between autophagy impairment and translational errors

open access: yesFEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk   +11 more
wiley   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

open access: yesFEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge   +6 more
wiley   +1 more source

Translation of a book of evidence and its impact on a criminal trial - A case study [PDF]

open access: yes, 2012
Interpreting in a legal setting in Ireland is not subject to any regulation. Police and court interpreters are neither certified nor tested. The current study aims to analyse the impact on a criminal trial of unqualified interpreters’ assistance in the ...
Jarmolowska, Karolina
core   +1 more source

Wordplay-based humor

open access: yesThe European Journal of Humour Research
Translating humour is comparable to working with poetry: one has to make sacrifices for the sake of equivalence. The task is further complicated when humour is anchored in multiple communication channels, such as the verbal and visual ones.
Kateryna Pilyarchuk
doaj   +1 more source

Artificial molecular machines and motors—Design and control of nanoscale motion

open access: yesFEBS Letters, EarlyView.
Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley   +1 more source

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