Results 91 to 100 of about 14,098,106 (309)

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

FEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg, Martine Hjeltnes, Josephine Krieger, Joshua E. Elias, Maria Stensland, Kristian Holm, Xiaojun Jiang, Chuki Khangsar, Tuula A. Nyman, Arthur Kaser, Johannes R. Hov, Tom H. Karlsen, Nicole C. Kaneider, Frode L. Jahnsen, Georg Schneditz   +14 more
wiley   +1 more source

Translating Creative Texts through Machine Translation: Deepl vs. Google Translate

Together with advancements in technology, there is an ongoing change in Translation Studies as more and more technological tools are being developed and implemented.
Sırkıntı, Hulisi Alp, Sırkıntı, Halise Gülmüş   +1 more
core   +1 more source

Word and Image: Theoretical and Methodological Approaches [PDF]

, 2014
The eleven articles collected in this volume approach the relationship between word and image from original angles, presenting a wide array of topics and methodologies from literary studies to cultural and translation studies.
Höglund, Mikko, Miettinen, Mervi, Kakko, Tommi, Rickman, Paul, Parviainen, Hanna   +4 more
core  

Association Between Machine Translation Post-Editing and Post-Editors’ Cognition: A Three-Level Meta-Analysis Based on Eye-Tracking Evidence

Behavioral Sciences
Prior research has overlooked interdependent effect sizes and moderating factors between machine translation post-editing (MTPE) and the post-editor’s cognition. To fill this void, the study employs a three-level meta-analysis. A total of 19 high-quality
Feng Wang, Hong Xie, Xiang Zhang
doaj   +1 more source

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

FEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas, Shahoon Khan, Abhishek Sharma, Byoungchun Lee, Savraj S. Grewal   +4 more
wiley   +1 more source

The Qualities of Literary Machine Translation

, 2022
This paper argues that an essential element affecting literary translation – the structure of narrative discourse – has been overlooked in research on literary MT systems so far.
Taivalkoski-Shilov Kristiina
core  

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Epigenetic reprogramming of lineage switching in cancer

FEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı, Burcu Akman, Ezgi Bağırsakçı, Nese Atabey, Serap Erkek‐Ozhan   +4 more
wiley   +1 more source

Translators' Agency in Persian Fansubbed Movies: A Paratextual Analysis

Critical Literary Studies
Drawing upon the notion of ‘paratextual agency’ (Paloposki, “Limits of Freedom” 191), the current study investigated the agency of the Iranian fansubbers.
Nima Noushmand , Milad Miraki
doaj   +1 more source