Results 241 to 250 of about 258,884 (313)

Multifunctional Gold Nanocluster‐Based PROTAC System for Targeted Degradation of Phosphorylated Tau and Modulation of Neuroinflammation in Alzheimer's Disease

Advanced Functional Materials, EarlyView.
We present a novel proteolysis‐targeting chimera (PROTAC) system conjugated to lipoic acid gold nanoclusters (PLANC), designed to degrade pTau, regulate inflammatory signaling, and effectively traverse the blood‐brain barrier (BBB). PLANC degraded pTau at various phosphorylation sites, with mechanistic studies confirming proteasome‐mediated degradation
Sarah Nevins, Callan D. McLoughlin, Wan‐Kyu Ko, Hye Kyu Choi, Brandon Conklin, Joshua B. Stein, Yannan Hou, Hongwon Kim, Rohan Khulbe, Ki‐Bum Lee   +9 more
wiley   +1 more source

GABARAPL1 is important for the activation of HRI during eIF2α phosphorylation-dependent stress response to sodium arsenite. [PDF]

Sci Rep
Campenet S, Lamarre M, Durand J, Perez V, Peixoto P, Delage-Mourroux R, Guittaut M, Baguet A, Despouy G.   +8 more
europepmc   +1 more source

Designing Stable Periodic Magnetization Textures by Tailoring Anisotropies and Applying Geometrical Transformation

Advanced Functional Materials, EarlyView.
This work explores the possibility to design stable periodic magnetization textures by transforming a 2D film into a rolled‐up 3D architecture and back. In case of an isotropic exchange‐biased layer architecture, the magnetization encoded in the 3D state evolves into a spin‐spiral pattern with controlled periodicity after unrolling.
Aman Singh, Ivan Soldatov, Rudolf Schäfer, Volker Neu   +3 more
wiley   +1 more source

Infrared Near-Field Microscopy as a Platform for Nanoscale Biomedical Spectroscopy and Imaging. [PDF]

ACS Appl Mater Interfaces
Deng H, Zhao X, Na X, Liu A, Cheng R, Jiang F, Zhang Q, Gao F, Wu H, Zhang T, Ma W, Deng L.   +11 more
europepmc   +1 more source

Translation techniques of legal texts and forensic linguistics

, 2011
Irina N. Meshkova, Мешкова Ирина Николаевна   +1 more
openalex   +1 more source

Low‐Profile, High‐Gain GRIN RF Lenses via Multi‐Material Vat Photopolymerization

Advanced Functional Materials, EarlyView.
We investigate the opportunity of leveraging multi‐material vat photopolymerization printing to manufacture intricate lenses exhibiting permittivity gradients that can increase signal gain in transmitted radiofrequency signals in the X‐ and Ku‐bands. Lenses produced with more distinct low‐loss materials (up to 5) can deliver an 18 dB signal gain with a
Lawrence Romangsuriat, Alexander Peraire‐Bueno, A. John Hart, Randall M. Erb   +3 more
wiley   +1 more source

Clinical outcomes of uni-portal non-coaxial spinal endoscopic surgery versus unilateral biportal endoscopic surgery for lumbar spinal stenosis: a retrospective cohort study. [PDF]

Front Surg
Cai XM, Li GS, Nie XY, Liu D, Xiao CL, Zhao M, Song E, Zhou JJ.   +7 more
europepmc   +1 more source

THE NOTION OF TRANSLATION TECHNIQUES IN AUDIOVISUAL TRANSLATION

openaire   +2 more sources

Thermally Pre‐Formed Reconfigurable Resistive Random‐Access Memory Crossbar Arrays: A Dual‐Mode Platform for Robust Physically Unclonable Functions and In‐Memory Computing

Advanced Functional Materials, EarlyView.
A reconfigurable RRAM platform utilizing thermally pre‐formed filaments (TPFs) is developed to realize robust hardware security. By exploiting the thermodynamic stochasticity of TPFs, exceptionally reliable physically unclonable functions (PUFs) are achieved.
Seongbin Kwon, Taewon Lee, Dohyeong Kim, Sungmin Hwang, Sungjoon Kim   +4 more
wiley   +1 more source

Micro-Stress Support-Enhanced Two-Plate Shearing Absolute Testing for Φ800 mm Interferometers. [PDF]

Sensors (Basel)
Zhao Z, Zhao Z, Fu Y, Wang J, Zhang Z, Zhao Y.   +5 more
europepmc   +1 more source