Results 121 to 130 of about 9,525,540 (330)
PharmaceuticsCancer remains a significant challenge for public healthcare systems worldwide. Within the realm of cancer treatment, considerable attention is focused on understanding the tumor microenvironment (TME)—the complex network of non-cancerous elements ...
Alyona B. Kuznetsova +4 more
doaj +1 more source
Design of Attitude Control System of an Axisymmetric Satellite with Gravity Gradient Stabilization and Slow Spinning about Yaw Axis [PDF]
فصلنامه علوم و فناوری فضایی, 2008 In this paper, attitude control system of an axisymmetric satellite will be designed in such a way that required stability is provided with slow spinning about yaw axis.
H. Bolandi, B. Ghorbani Vaghei
doaj
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Rule-based cloud service localisation [PDF]
, 2013 The fundamental purpose of cloud computing is the ability to quickly provide software and hardware resources to global users. The main aim of cloud service localisation is to provide a method for facilitating the internationalisation and localisation of ...
Collins, Luke +2 more
core
Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
Molecular Oncology, EarlyView.We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source
ELECTRONIC CORPORA IN TRANSLATION BOOTCAT-BOOTSTRAPPING CORPORA AND TERMS FROM THE WEB [PDF]
In the new world of technology, the translation profession, like other disciplines, cannot be deprived of modern tools such as electronic corpora. Recently, large monolingual, comparable and parallel corpora have played a crucial role in solving various ...
Elena Museanu, Mariana Coanca
core
Molecular Oncology, EarlyView.The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola +12 more
wiley +1 more source
, 2012 A human-computer interface is developed to provide services of computer assisted machine translation (CAT) and computer assisted transcription of handwritten text images (CATTI). The back-end machine translation (MT) and handwritten text recognition (HTR)
Ocampo Sepúlveda, Jorge Carlos
core
Hormone-Mediated Gene-Specific Translation Regulation [PDF]
, 2016 The central role of translation regulation in the control of critical cellular processes has long been recognized. Yet the systematic exploration of quantitative changes in translation at a genome-wide scale in response to specific stimuli has only ...
Alonso, José +4 more
core