Results 271 to 280 of about 617,976 (302)
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Diversity in translational regulation
Current Opinion in Cell Biology, 2001Translational control of individual mRNAs relies on cis-regulatory elements, which are often found in the 3' untranslated region. The best characterized of these regulate cytoplasmic polyadenylation, and much of this process can now be defined in terms of molecular interactions, protein modifications and their consequences.
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Translation and translational regulation in chloroplasts
2007The translation mechanism of chloroplast mRNAs originated as prokaryotic-type, but has sinceevolved considerably. Chloroplast translation became, in large part, uncoupled from transcription,and turned into a highly regulated process. Concomitantly, chloroplast ribosomes, general translationfactors, and transcripts changed substantially from their ...
Hadas Peled-Zehavi, Avihai Danon
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Ribosomal tunnel and translation regulation
Biochemistry (Moscow), 2010This review describes the results of recent studies of the ribosomal tunnel (RT), the major function of which is to allow the smooth passage of nascent polypeptides with different sequences from the peptidyl transferase center of the ribosome to the tunnel exit, where the folding of protein molecules begins.
A A, Bogdanov +4 more
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Seeds: A Unique System to Study Translational Regulation
Trends in Plant Science, 2019 Seeds accumulate mRNA during their development and have the ability to store these mRNAs over extended periods of time. On imbibition, seeds transform from a quiescent dry state (no translation) to a fully active metabolic state, and selectively ...
Nikita Sajeev +2 more
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Regulation of Translation by Hydrogen Peroxide
Antioxidants & Redox Signaling, 2011Cells must be able to maintain their intracellular homeostasis in the face of changing conditions. Typically, they respond by invoking complex regulatory mechanisms, including a global inhibition of translation. This reduction in protein synthesis may prevent continued gene expression during potentially error-prone conditions as ...
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Control and regulation of mRNA translation
Biochemical Society Transactions, 2014Translational control is central to the gene expression pathway and was the focus of the 2013 annual Translation UK meeting held at the University of Kent. The meeting brought together scientists at all career stages to present and discuss research in the mRNA translation field, with an emphasis on the presentations on the research of early career ...
Emma J, Mead +4 more
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Regulation of Translation by Poliovirus
1987Publisher Summary This chapter discusses the regulation of translation by poliovirus. It emphasizes recent developments—especially with regard to the function of cap binding proteins—in translation initiation and their modification following poliovirus infection. There is currently a general agreement about the mechanism by which poliovirus infection
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eIF2α phosphorylation and the regulation of translation
Current Genetics, 2019We discuss novel insight into the role and consequences of the phosphorylation of the translation initiation factor eIF2α in the context of stress responses and cell-cycle regulation. eIF2α is centrally located to regulate translation and its phosphorylation in response to different environmental challenges is one of the best characterized stress ...
Erik Boye, Beáta Grallert
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Synthesis of the translational apparatus is regulated at the translational level
European Journal of Biochemistry, 2000The synthesis of many mammalian proteins associated with the translational apparatus is selectively regulated by mitogenic and nutritional stimuli, at the translational level. The apparent advantages of the regulation of gene expression at the translational level are the speed and the readily reversible nature of the response to altering physiological ...
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Translational Regulation in the Mammalian Oocyte
2017Fully grown oocytes arrest meiosis at prophase I and deposit maternal RNAs. A subset of maternal transcripts is stored in a dormant state in the oocyte, and the timely driven translation of specific mRNAs guides meiotic progression, the oocyte-embryo transition, and early embryo development.
Andrej, Susor, Michal, Kubelka
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