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Translational regulation of mitochondrial biogenesis
Biochemical Society Transactions, 2016Mitochondria are generated by the expression of genes on both nuclear and mitochondrial genome. Mitochondrial biogenesis is highly plastic in response to cellular energy demand, developmental signals and environmental stimuli. Mechanistic target of rapamycin (mTOR) pathway regulates mitochondrial biogenesis to co-ordinate energy homeostasis with cell ...
Yi, Zhang, Hong, Xu
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Translation regulation of mammalian selenoproteins
Biochimica et Biophysica Acta (BBA) - General Subjects, 2018Interest in selenium research has considerably grown over the last decades owing to the association of selenium deficiencies with an increased risk of several human diseases, including cancers, cardiovascular disorders and infectious diseases. The discovery of a genetically encoded 21st amino acid, selenocysteine, is a fascinating breakthrough in ...
Vindry, Caroline +2 more
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Regulation of local mRNA translation
Current Opinion in Cell Biology, 2004Regulated local mRNA translation is one mechanism cells employ to concentrate proteins in particular locations. However, cells use many different strategies to accomplish this task; for example, some mRNAs are destroyed in regions where they are not wanted, other mRNAs are repressed in areas where their translation would be deleterious, and yet other ...
Yi-Shuian, Huang, Joel D, Richter
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1979
Wir haben bereits eine Vielzahl regulierender Faktoren der Proteinbiosynthese kennengelernt und haben auch gesehen, das die Synthese bereits bei der Blok-kade eines einzigen Schrittes eingestellt wird. Regulation findet auf vielen Ebenen statt, und die meisten sind im Detail noch gar nicht aufgeklart. Das beginnt bereits bei der Regulation der Synthese
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Wir haben bereits eine Vielzahl regulierender Faktoren der Proteinbiosynthese kennengelernt und haben auch gesehen, das die Synthese bereits bei der Blok-kade eines einzigen Schrittes eingestellt wird. Regulation findet auf vielen Ebenen statt, und die meisten sind im Detail noch gar nicht aufgeklart. Das beginnt bereits bei der Regulation der Synthese
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Translational regulation by ABC systems
Research in Microbiology, 2001Elongation factor 3 is a cytosolic protein required by the fungal ribosomes for in vitro protein synthesis and for in vivo growth. EF-3 stimulates binding of EF-1:GTP:aa-tRNA ternary complex to the ribosomal A site by facilitated release of the deacylated tRNA from the E site. The reaction requires ATP hydrolysis. EF-3 contains two ATP binding sequence
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The molecular principles of gene regulation by Polycomb repressive complexes
Nature Reviews Molecular Cell Biology, 2021Neil P Blackledge, Robert J Klose
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Translating Nrf2 Regulated Translation
Free Radical Biology and Medicine, 2019openaire +1 more source
Histone post-translational modifications — cause and consequence of genome function
Nature Reviews Genetics, 2022Andrew J Bannister +2 more
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