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Humanized mice in translational biomedical research

Nature Reviews Immunology, 2007
The culmination of decades of research on humanized mice is leading to advances in our understanding of human haematopoiesis, innate and adaptive immunity, autoimmunity, infectious diseases, cancer biology and regenerative medicine. In this Review, we discuss the development of these new generations of humanized mice, how they will facilitate ...
Shultz, L D, Ishikawa, F, Greiner, D L
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Improving translational biomedical research in Chile

The Lancet, 2007
Several international initiatives have tried to set bio medical research as a cornerstone for health improvement in low-income and middle-income countries. Historically contributions from private institutions such as the Rockefeller Foundation programme on tropical diseases and public health had a visible effect in Latin America and Asia during the ...
JimĂ©nez, J.   +1 more
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Translational Bioinformatics and Clinical Research (Biomedical) Informatics

Surgical Pathology Clinics, 2015
Translational bioinformatics and clinical research (biomedical) informatics are the primary domains related to informatics activities that support translational research. Translational bioinformatics focuses on computational techniques in genetics, molecular biology, and systems biology.
S Joseph, Sirintrapun   +5 more
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Reengineering Biomedical Translational Research with Engineering Ethics

Science and Engineering Ethics, 2014
It is widely accepted that translational research practitioners need to acquire special skills and knowledge that will enable them to anticipate, analyze, and manage a range of ethical issues. While there is a small but growing literature that addresses the ethics of translational research, there is a dearth of scholarship regarding how this might ...
Mary E, Sunderland, Rahul Uday, Nayak
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