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Translational Bioinformatics and Clinical Research (Biomedical) Informatics
Surgical Pathology Clinics, 2015Translational bioinformatics and clinical research (biomedical) informatics are the primary domains related to informatics activities that support translational research. Translational bioinformatics focuses on computational techniques in genetics, molecular biology, and systems biology.
Nikolaus Schultz +2 more
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The Use of Translational Research Platforms in Clinical and Biomedical Data Exploration
Advances in Experimental Medicine and Biology, 2017The rise of precision medicine combined with the variety of biomedical data sources and their heterogeneous nature make the integration and exploration of information that they retain more complicated. In light of these issues, translational research platforms were developed as a promising solution.
Antigoni Avramouli
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Research software engineering accelerates the translation of biomedical research for health [PDF]
Research software engineering is central to data-driven biomedical research, but its role is often undervalued and poorly understood.
David Horsfall +5 more
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Keeping track of translational research is essential to evaluating the performance of programs on translational medicine. Despite several indicators in previous studies, a consensus measure is still needed to represent the translational features of ...
Wei Lu, Tang Xuli
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Improving translational biomedical research in Chile
The Lancet, 2007Several international initiatives have tried to set bio medical research as a cornerstone for health improvement in low-income and middle-income countries. Historically contributions from private institutions such as the Rockefeller Foundation programme on tropical diseases and public health had a visible effect in Latin America and Asia during the ...
Jiménez, J. +1 more
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Transgenic pigs as models for translational biomedical research
Journal of Molecular Medicine, 2010The translation of novel discoveries from basic research to clinical application is a long, often inefficient, and thus costly process. Accordingly, the process of drug development requires optimization both for economic and for ethical reasons, in order to provide patients with appropriate treatments in a reasonable time frame.
Bernhard, Aigner +6 more
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Reengineering Biomedical Translational Research with Engineering Ethics
Science and Engineering Ethics, 2014It is widely accepted that translational research practitioners need to acquire special skills and knowledge that will enable them to anticipate, analyze, and manage a range of ethical issues. While there is a small but growing literature that addresses the ethics of translational research, there is a dearth of scholarship regarding how this might ...
Mary E. Sunderland, Rahul Uday Nayak
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Translational science: a survey of US biomedical researchers’ perspectives and practices
Lab Animal, 2021This national survey aimed to identify how biomedical researchers using vertebrate animals viewed issues of significance for translational science, including oversight and public engagement, and to analyze how researcher characteristics and animal model choice correlate with those views.
Rebecca L. Walker +3 more
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Ultrasmall silica nanoparticles in translational biomedical research: Overview and outlook
Advanced Drug Delivery Reviews, 2023The exemplary progress of silica nanotechnology has attracted extensive attention across a range of biomedical applications such as diagnostics and imaging, drug delivery, and therapy of cancer and other diseases. Ultrasmall silica nanoparticles (USNs) have emerged as a particularly promising class demonstrating unique properties that are especially ...
Neetu, Singh, Sixiang, Shi, Shreya, Goel
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Translational Research and Biomedical Informatics
2009A critical need exists to address real issues that appear when a physician is faced with a patient and the need to make clinical decisions that will impact the patient, their quality life, and those of the patient's family. Bridging this gap between the clinical need and the available technologies, clinical data, and clinician input is the role that ...
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