Translational research in medicine
Translational medicine is a medical practice based on interventional epidemiology. It is regarded by its proponents as a natural progression from Evidence-Based Medicine.
Bakir Mehić
doaj +1 more source
Translational Research Communication: a new experience [PDF]
Academics are like optical fibre. They generate communication about their research along exceptionally narrow channels. Their research communication is almost exclusively focused on their discipline – to their conferences and their journals.
Hofmeyr, Sally
core
Aligning the top-level of SNOMED-CT with Basic Formal Ontology [PDF]
Effective translational research requires automated analysis of large datasets collected by multiple researchers working at multiple locations. Reliable, machine interpretation of-—and reasoning with—-large datasets assembled at different ...
William Hogan
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ABSTRACT Objective To evaluate the diagnostic yield and utility of universal paired tumor–normal multigene panel sequencing in newly diagnosed pediatric solid and central nervous system (CNS) tumor patients and to compare the detection of germline pathogenic/likely pathogenic variants (PV/LPVs) against established clinical referral criteria for cancer ...
Natalie Waligorski +9 more
wiley +1 more source
Embracing complexity: theory, cases and the future of bioethics [PDF]
This paper reflects on the relationship between theory and practice in bioethics, by using various concepts drawn from debates on innovation in healthcare research—in particular debates around how best to connect up blue skies ‘basic’ research with ...
Wilson, J
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Prevalence and Trajectory of Household Material Hardship Among Children With Advanced Cancer
ABSTRACT Background/Objectives Families of children with advanced cancer living in poverty experience inferior outcomes including poor parent mental health and worse child quality of life. Household material hardship (HMH: food, housing, transportation, and/or utility insecurity) is a modifiable poverty exposure—and potential intervention target—that ...
Sarah Wright +13 more
wiley +1 more source
Excellence in Community-Engaged Research at Virginia Commonwealth University: A Compendium of Case Studies Developed Through a Faculty Learning Community [PDF]
Since 2005, the Center for Teaching Excellence (CTE) at VCU has offered faculty learning communities (FLC) on a variety of teaching and learning issues.
Center for Clinical and Translational Research +1 more
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Acute hydrogen sulfide-induced neuropathology and neurological sequelae: challenges for translational neuroprotective research. [PDF]
Hydrogen sulfide (H2 S), the gas with the odor of rotten eggs, was formally discovered in 1777, over 239 years ago. For many years, it was considered an environmental pollutant and a health concern only in occupational settings. Recently, however, it was
Anantharam, Poojya +4 more
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Organoids in pediatric cancer research
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
Enhancing translational medical research through proof-of-concept services: clinicians’ perspectives
Although the proof-of-concept (POC) phase is critical for the success of translational medical research (TMR), its use remains limited, and clinicians are frequently uncertain about how to seek assistance from POC teams when experiencing difficulties ...
Lei Yuan +7 more
doaj +1 more source

