Results 51 to 60 of about 51,482,470 (263)

Translational research in medicine

Biomolecules & Biomedicine, 2011
Translational medicine is a medical practice based on interventional epidemiology. It is regarded by its proponents as a natural progression from Evidence-Based Medicine.
Bakir Mehić
doaj   +1 more source

Imaging in translational cancer research

Cancer Biology & Medicine, 2022
This review is aimed at presenting some of the recent developments in translational cancer imaging research, with a focus on novel, recently established, or soon to be established cross-sectional imaging techniques for computed tomography (CT), magnetic ...
Felix T. Kurz, Heinz-Peter Schlemmer
doaj   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

FEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar, Xinqi Yan, Lucas F. Jansen Klomp, Stefano Schivo, Janine N. Post   +4 more
wiley   +1 more source

Flow over a cylinder subjected to combined translational and rotational oscillations [PDF]

, 2012
The experimental research reported here employs particle image velocimetry to extend the study of Nazarinia et al. (2009a), recording detailed vorticity fields in the near-wake of a circular cylinder undergoing combined translational and rotational ...
Mark C. Thompson, Mehdi Nazarinia, Lo Jacono, David, Thompson, Mark C., John Sheridan, David Lo Jacono, Nazarinia, Mehdi, Sheridan, John, Nazarinia, Mehdi; id_orcid   +8 more
core   +1 more source

Echocardiography in translational research

, 2015
Departement Klinische Forschung, Forschungsgruppe Herz- und ...
Tevaearai, Hendrik, Monney, P, Jeanrenaud, X, Locca, D   +3 more
core   +1 more source

Steps toward developing an algorithm to facilitate recognition of translational science

Journal of Clinical and Translational Science
Introduction: In preparing for our Clinical and Translational Science Award (CTSA) UM1 application, we recognized the need to develop a shared understanding of the distinctions between translational science (TS) and translational research (TR).
Paul J. Martin, Brian E. Saelens, Theodore Johnson, Mark Harniss, Tumaini R. Coker, Erin Abu-Rish Blakeney, Nina Isoherranen, Tong Sun, Nisha Bansal, Stephanie J. Lee, John Amory, Naomi Kaku, Melissa Vaught   +12 more
doaj   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

FEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens, Brendan W. Chandler, Anna M. Schmoker, Jaye L. Weinert, Charlotte A. Kearns, Warren T. Yacawych, Amila Šemić, Alicia M. Ebert, Bryan A. Ballif   +8 more
wiley   +1 more source

A quantitative estimation of the global translational activity in logarithmically growing yeast cells. [PDF]

, 2008
BACKGROUND: Translation of messenger mRNAs makes significant contributions to the control of gene expression in all eukaryotes. Because translational control often involves fractional changes in translational activity, good quantitative descriptions of ...
von der Haar, Tobias, Tobias von der Haar   +1 more
core   +1 more source

An innovative educational program for addressing health disparities in translational cancer research.

, 2023
North Carolina Central University (NCCU) and Duke Cancer Institute implemented an NCI-funded Translational Cancer Disparities Research Partnership to enhance translational cancer research, increase the pool of underrepresented racial and ethnic group ...
Barrett, Nadine J, Gathings, MJ, Devi, Gayathri R, Patierno, Steven R, Hough, Holly J, Oldham, Carla E, Williams, Kevin P   +6 more
core   +1 more source