Results 41 to 50 of about 1,837,633 (293)
Translational research as an integral part of work–based learning [PDF]
, 2019 Shelagh Keogh, Northumbria University, UK This paper explores the concept of translational research as an appropriate strategy for work based learning.
Fulton, John, Keogh, Shelagh
core
The Promotoer: a successful story of translational research in BCI for motor rehabilitation [PDF]
, 2017 Several groups have recently demonstrated in the context of randomized controlled trials (RCTs) how sensorimotor Brain-Computer Interface (BCI) systems can be beneficial for post-stroke motor recovery.
Cincotti, Febo +3 more
core +1 more source
Reciprocal control of viral infection and phosphoinositide dynamics
FEBS Letters, EarlyView.Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
Translational PET imaging research
Neurobiology of Disease, 2014 The goal of any early central nervous system (CNS) drug development program is always to test the mechanism and not the molecule in order to support additional research investments in late phase clinical trials.
Richard J. Hargreaves +1 more
doaj +1 more source
Concept Mapping to Develop a Framework for Characterizing Electronic Data Capture (EDC) Systems [PDF]
, 2008 CTSAs have brought about a push to find better EDC systems, which facilitate translational research. Based on the data management needs of a specific clinical/translational research lab, concept mapping was used to create a framework to evaluate EDCs ...
Anderson, Nicholas R +3 more
core +1 more source
Technology-based rehabilitation to improve communication after acquired brain injury [PDF]
, 2017 The utilization of technology has allowed for several advances in aphasia rehabilitation for individuals with acquired brain injury. Thirty-one previous studies that provide technology-based language or language and cognitive rehabilitation are examined ...
Des Roches, Carrie A., Kiran, Swathi
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Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Journal of Clinical and Translational ScienceRecent years have seen increasing focus, including by the National Institutes for Health (NIH), on developing the field of translational science (TS). TS focuses on improving the process of translational research (TR), including generating knowledge that
Jessica Sperling +8 more
doaj +1 more source
Taurine as a biomarker for aging: A new avenue for translational research
Advances in Biomarker Sciences and Technology, 2023 The physiologic and irreversible process of ageing is accompanied by a wide range of structural and functional shifts at multiple different levels.
Animesh Acharjee
doaj +1 more source
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source