Results 81 to 90 of about 51,482,470 (263)

Innovative drug delivery and translational research by emerging leaders in the field. [PDF]

open access: yes
The field of drug delivery continues to be at the forefront of innovation, driven by the relentless pursuit of more effec- tive, targeted, and safer therapies.
Kumeria, Tushar   +2 more
core   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

open access: yesFEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge   +6 more
wiley   +1 more source

Growing Translational Plant Sciences

open access: yes, 2015
The annual magazine for the Virginia Tech Translational Plant Sciences (TPS) graduate program, formerly Molecular Plant Sciences (MPS)
Translational Plant Sciences   +1 more
core  

Recommendations for addressing the translational gap between experimental and clinical research on amyloid diseases [Elektronisk resurs]

open access: yes, 2022
This paper is a report of recommendations for addressing translational challenges in amyloid disease research. They were developed during and following an international online workshop organized by the LINXS Institute of Advanced Neutron and X-Ray ...
Fodera, Vito,   +8 more
core   +1 more source

Translational research in psychiatry

open access: yesIndustrial Psychiatry Journal
Translational research in psychiatry bridges the gap between basic scientific discoveries and clinical applications, aiming to improve the diagnosis, treatment, and prevention of mental illnesses.
Vinay Singh Chauhan, Markanday Sharma
doaj   +1 more source

Artificial molecular machines and motors—Design and control of nanoscale motion

open access: yesFEBS Letters, EarlyView.
Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley   +1 more source

Growing Translational Plant Sciences

open access: yes, 2016
The annual magazine for the Virginia Tech Translational Plant Sciences (TPS) graduate program, formerly Molecular Plant Sciences (MPS)
Translational Plant Sciences   +1 more
core  

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

open access: yesFEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise   +5 more
wiley   +1 more source

Overcoming the translational roadblocks: a cancer care and research model

open access: yesClinical and Translational Medicine, 2014
There are many challenges to the process of translating the knowledge gained in the laboratory into new clinical approaches that can meet the needs of patients, clinicians and the wider community. We describe here an initiative that has borrowed concepts
Lauren Braun   +2 more
doaj   +1 more source

A team-based translational journal club: Understanding the translational research highway

open access: yesJournal of Clinical and Translational Science, 2019
The mission of the National Center for Advancing Translational Science (NCATS) is to catalyze the generation of innovative methods and technologies that will enhance the development, testing, and implementation of diagnostics and therapeutics across a ...
Carol Feghali-Bostwick   +4 more
doaj   +1 more source

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