Results 91 to 100 of about 1,185,385 (293)
A new vision of definition, commentary, and understanding in clinical and translational medicine
Clinical and Translational Medicine, 2012 There is growing evidence to the importance of translational science and medicine in the improvement of patient outcome, even though the definitions of translational science, translational medicine, and clinical and translational medicine need to be ...
Xiangdong Wang
doaj +1 more source
Translational Science Research: Towards Better Health
Biomolecules & Biomedicine, 2009 Even though it is considered a 21st century term, translational research has been present for much longer. Idea of translating experimental discovery to its’ clinical application and use is old as research itself.
Emir Festic, Ognjen Gajic
doaj +1 more source
Molecular Oncology, EarlyView.Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon +9 more
wiley +1 more source
Journal of Clinical and Translational ScienceObjectives/Goals: This study illuminates the efforts of a Clinical and Translational Science Award (CTSA) Hub to share stories of its aspirations, challenges, successes, opportunities, and impact when pursuing its complex goals, and how storytelling ...
Boris Volkov +1 more
doaj +1 more source
Family science has been doing translational science since before it came into vogue. Nevertheless, the field has been subjected to the same forces in the broader academy that have created a widening chasm between discovery and practice. Thus, the primary
core
Molecular Oncology, EarlyView.Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source
172 Collaborations between translational science programs and academic health sciences libraries
Journal of Clinical and Translational ScienceObjectives/Goals: Collaborations between translational science programs and academic health sciences libraries can enhance research impact by improving efficiency, leveraging diverse professional expertise, and expanding opportunities for collaboration ...
Bart Ragon +6 more
doaj +1 more source
Finding Translational Science Publications in MEDLINE/PubMed with Translational Science Filters
Clinical and Translational Science, 2011 AbstractTranslational Science Search (TSS; http://tscience.nlm.nih.gov) is a web application for finding MEDLINE/PubMed journal articles that are regarded by their authors as novel, promising, or may have potential clinical application. A set of “translational” filters and related terms was created by reviewing journal articles published in clinical ...
Paul, Fontelo, Fang, Liu
openaire +3 more sources
Center for Clinical and Translational Science Community Engagement Program [PDF]
, 2017 IMPACT. 1: We have over 40 community partners from 18 counties in Central and Southeastern Ohio, including churches, schools, nursing homes, philanthropy groups, OSU extension offices, county health departments, and civic groups. -- 2.
Grever, Jeff
core
The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity
Molecular Oncology, EarlyView.Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli +7 more
wiley +1 more source