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UMCCTS Newsletter, September 2025 [PDF]

open access: yes
This is the September 2025 issue of the UMass Center for Clinical and Translational Science Newsletter containing news and events of interest.Supported by the National Center for Advancing Translational Sciences, National Institutes of Health, through ...
UMass Center for Clinical and Translational Science
core   +1 more source

Decoding the dynamic extracellular matrix in cancer—3D models and bioscaffolds rewire the rules of tumor progression

open access: yesFEBS Letters, EarlyView.
Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani   +3 more
wiley   +1 more source

UMCCTS Newsletter, November 2024 [PDF]

open access: yes
This is the Novembr 2024 issue of the UMass Center for Clinical and Translational Science Newsletter containing news and events of interest.Supported by the National Center for Advancing Translational Sciences, National Institutes of Health, through ...
UMass Center for Clinical and Translational Science
core   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

UMCCTS Newsletter, July 2024 [PDF]

open access: yes
This is the July 2024 issue of the UMass Center for Clinical and Translational Science Newsletter containing news and events of interest.Supported by the National Center for Advancing Translational Sciences, National Institutes of Health, through Grants ...
UMass Center for Clinical and Translational Science
core   +1 more source

Poster Program: 2014 UMass Center for Clinical and Translational Science Research Retreat [PDF]

open access: yes, 2014
List of posters presented during the Poster Session at the fifth annual UMass Center for Clinical and Translational Science Research Retreat, held Tuesday, May 20, 2014, at the Albert Sherman Center at the University of Massachusetts Medical School ...
UMass Center for Clinical and Translational Science Research Retreat
core   +1 more source

159 Community Engagement (CE) Brokers: Diversity and the Science of CE

open access: yes, 2022
OBJECTIVES/GOALS: Since 2013, managers of community engagement (CE) programs across the Clinical and Translational Science Award (CTSA) consortium funded by the National Center for Advancing Translational Sciences (NCATS) have convened monthly to build ...
Piechowski, Patricia   +4 more
core   +1 more source

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

UMCCTS Newsletter, February 2025

open access: yes
This is the February 2025 issue of the UMass Center for Clinical and Translational Science Newsletter containing news and events of interest.Supported by the National Center for Advancing Translational Sciences, National Institutes of Health, through ...
UMass Center for Clinical and Translational Science
core   +1 more source

Translation and Science [PDF]

open access: yesMeta, 2002
Both the discourse and practice of science are fundamentally related to the idea of translation. The multi-semiotic nature of scientific texts makes this explicitly visible. Even at the foundational level, science is possible only because it sees the world as the given original; the response of science to the original-world shares ...
openaire   +2 more sources

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