Results 61 to 70 of about 699,897 (304)
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Journal of Clinical and Translational ScienceOrganizations supporting translational research and translational science, including Clinical and Translational Science Award (CTSA) hubs, provide a diverse and often changing array of resources, support, and services to a myriad of researchers and ...
Jessica Sperling +4 more
doaj +1 more source
FEBS Letters, EarlyView.Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
UMCCTS Newsletter, May 2025 [PDF]
This is the May 2025 issue of the UMass Center for Clinical and Translational Science Newsletter containing news and events of interest.Supported by the National Center for Advancing Translational Sciences, National Institutes of Health, through Grants ...
UMass Center for Clinical and Translational Science
core +2 more sources
Mini Symposia Program: 2014 UMass Center for Clinical and Translational Science Research Retreat [PDF]
, 2014 Mini Symposia Program for the fifth annual UMass Center for Clinical and Translational Science Research Retreat, held Tuesday, May 20, 2014 at the Albert Sherman Center, University of Massachusetts Medical School, Worcester, MA.
UMass Center for Clinical and Translational Science
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An innovative educational program for addressing health disparities in translational cancer research. [PDF]
, 2023 North Carolina Central University (NCCU) and Duke Cancer Institute implemented an NCI-funded Translational Cancer Disparities Research Partnership to enhance translational cancer research, increase the pool of underrepresented racial and ethnic group ...
Barrett, Nadine J +6 more
core +1 more source
Journal of Clinical and Translational Science, 2021 As the need to tackle complex clinical and societal problems rises, researchers are increasingly taking on a translational approach. This approach, which seeks to integrate theories, methodologies, and frameworks from various disciplines across a team of
Sydney R. Begerowski +3 more
doaj +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
UMCCTS Newsletter, August 2024 [PDF]
This is the August 2024 issue of the UMass Center for Clinical and Translational Science Newsletter containing news and events of interest.Supported by the National Center for Advancing Translational Sciences, National Institutes of Health, through ...
UMass Center for Clinical and Translational Science
core +2 more sources
Poster Program: 2014 UMass Center for Clinical and Translational Science Research Retreat [PDF]
, 2014 List of posters presented during the Poster Session at the fifth annual UMass Center for Clinical and Translational Science Research Retreat, held Tuesday, May 20, 2014, at the Albert Sherman Center at the University of Massachusetts Medical School ...
UMass Center for Clinical and Translational Science Research Retreat
core +2 more sources