Results 101 to 110 of about 2,068,781 (331)

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

open access: yesFEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson   +7 more
wiley   +1 more source

Remembering the Dead: Electronic Literature as Memorial and Meme

open access: yesMatLit, 2018
This essay describes a multimedia memorial, Remembering the Dead, that seeks to remember victims of mass shootings in the United States of America. This elegiac work may be considered a diversity for electronic literature, specifically one focused on ...
John F. Barber
doaj   +1 more source

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

The Reception of Galician Performances and (Re)translations of Shakespeare

open access: yesMulticultural Shakespeare, 2017
This presentation will deal with the reception of performances, translations and retranslations of Shakespeare’s plays into the Galician language. As is well-known, Galician is a Romance language which historically shared a common origin with Portuguese ...
María Jesús Lorenzo-Modia
doaj   +1 more source

Book Translations As Idea Flows: The Effects of the Collapse of Communism on the Diffusion of Knowledge [PDF]

open access: yes
We use book translations as a new measure of international idea flows and study the effects of Communism’s collapse in Eastern Europe on these flows. Using novel data on 800,000 translations, we show that while translations between Communist languages ...
Isabelle Sin, Ran Abramitzky
core  

The Debt and Other Poems [PDF]

open access: yes, 2016
A selection of poems, translations, and imitations written from 2009 ...
Corbett, Kevin
core   +2 more sources

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

open access: yesMolecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts   +8 more
wiley   +1 more source

QUANTIZATION OF A CLASS OF PIECEWISE AFFINE TRANSFORMATIONS ON THE TORUS

open access: yes, 1995
We present a unified framework for the quantization of a family of discrete dynamical systems of varying degrees of "chaoticity". The systems to be quantized are piecewise affine maps on the two-torus, viewed as phase space, and include the automorphisms,
B. Eckhardt   +19 more
core   +1 more source

Adenosine‐to‐inosine editing of miR‐200b‐3p is associated with the progression of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira   +14 more
wiley   +1 more source

Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine

open access: yesMolecular Oncology, EarlyView.
The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu   +18 more
wiley   +1 more source

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