Results 101 to 110 of about 663,083 (245)
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Book Translations As Idea Flows: The Effects of the Collapse of Communism on the Diffusion of Knowledge [PDF]
We use book translations as a new measure of international idea flows and study the effects of Communism’s collapse in Eastern Europe on these flows. Using novel data on 800,000 translations, we show that while translations between Communist languages ...
Isabelle Sin, Ran Abramitzky
core
El milagro secreto de Emilio Renzi: Otra vuelta a la novela del porvenir
Cuadernos LIRICO, 2019 This article analyzes the effect of the publication of Los diarios de Emilio Renzi in the concept of Ricardo Piglia’s “novela del porvenir”. A partial reading of the Diarios is made next to several specific moments from Piglia’s work, in which the ...
Sergio Waisman
doaj +1 more source
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
Molecular Oncology, EarlyView.COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source
Translating Calvino, Calvino Translated, Calvino Translator
ACME, 2018 ACME, V. 71, N. 1 (2018)
openaire +2 more sources
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Seeing the wood for the trees: data-oriented translation [PDF]
, 2003 Data-Oriented Translation (DOT), which is based on Data-Oriented Parsing (DOP), comprises an experience-based approach to translation, where new translations are derived with reference to grammatical analyses of previous translations.
Hearne, Mary, Way, Andy
core +4 more sources
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Iranian Rehabilitation Journal, 2019 Objectives: The elderly residents of nursing homes experience falling at least once a year. The fear of falling influences the quality of life and causes limitations in their daily living activities.
Mahsa Fadavi-Ghaffari +4 more
doaj