Results 151 to 160 of about 56,063 (262)

The Health-Related Quality of Life and Putative Factors of Icelandic and American Youth with Multiple Disabilities Including Visual Impairments: A Preliminary Investigation. [PDF]

Children (Basel)
Brian A, Taliaferro A, Beach P, Lytle B, Pennell A, Lieberman L, Einarsson I.   +6 more
europepmc   +1 more source

MicroRNA‐375‐3p Targets Fatty Acid Synthase and Relish to Regulate Energy Allocation During Pupal Metamorphosis and Starvation

Advanced Science, EarlyView.
During pupal metamorphosis and starvation, elevated 20‐hydroxyecdysone (20E) and suppressed insulin trigger Forkhead box O (FOXO) nuclear translocation, enhancing miR‐375‐3p expression. This downregulates fatty acid synthase (FASN) and Relish, promoting lipid breakdown for energy while prioritizing antioxidant responses over immune functions to support
Peng Chen, Meiqi Cheng, Jianhui Wang, Jing Tang, Xiaoqiao Huang, Yusi Li, Huiling Zhou, Ling Zhang, Yi Dong, Chengjun Li, Bin Li   +10 more
wiley   +1 more source

Exploring the role of standards-based descriptors in promoting translation learners' metacognitive strategy use and translation performance. [PDF]

Front Psychol
Mei H, Chen Y.
europepmc   +1 more source

Mass Spectrometry Imaging‐Assisted Discovery of Gallotannin Biosynthetic Genes in the Root of Paeonia suffruticosa

Advanced Science, EarlyView.
An integrated approach combining mass spectrometry imaging, transcriptomics, and phylogenetic analysis facilitated the efficient identification of genes involved in gallotannin biosynthesis in Paeonia suffruticosa. As a result, a key UGT and several SCPL acyltransferases responsible for biosynthesizing pentagalloylglucose were successfully identified ...
Yushi Liu, Wenna Duan, Weiwei Tang, Yucheng Zhao, Bin Li   +4 more
wiley   +1 more source

Addressing activities related to food supplements in European pharmacists' codes of ethics: textual analysis and proposals for ethical standards. [PDF]

BMC Med Ethics
Toma A, Crișan O.
europepmc   +1 more source

Discovery of SKP2‐Recruiting PROTACs for Target Protein Degradation

Advanced Science, EarlyView.
Based on the SKP2‐targeting ligand SL1, we designed non‐covalent PROTACs by linking it with the BRD4 inhibitor JQ1 and the AR antagonist AL through a linker. These PROTACs successfully induced the ubiquitination of BRD4 and AR, followed by proteasome‐mediated degradation.
Guanjun Dong, Aima Huang, Ziqing Zhao, Bikai Lai, Xin Pan, Huiyu Yang, Xiaohan Xu, Tianwei Wang, Fangchen Zhao, Zhimin Zhang, Yongbo Xue, Guanjun Deng, Wenbin Deng, Jianwei Chen   +13 more
wiley   +1 more source

Community nurses' experiences with digital sensory interventions in remote primary care: a qualitative descriptive study of trust, privacy, and family dynamics. [PDF]

BMC Nurs
Alotaibi A.
europepmc   +1 more source

De Novo Design and Directed Evolution Refinement of Mirror‐Image Protein Binders Targeting Interleukin‐4

Advanced Science, EarlyView.
This study presents the de novo design and directed evolution of a mirror‐image D‐protein inhibitor targeting human interleukin‐4 (IL‐4). The engineered molecule exhibits nanomolar binding affinity for IL‐4 and effectively inhibits IL‐4–mediated signaling.
Liqing Xu, Yuxiang Ren, Tongyue Wang, Hongyong Li, Yue Yao, Lei Liu, Ke Sun, Peilong Lu   +7 more
wiley   +1 more source

Development and psychometric evaluation of the Japanese version of the Nurse Professional Competence Scale Short-Form. [PDF]

Belitung Nurs J
Tanabe S, Tanaka M, Arai Y, Matsuo K, Nakrem S, Gardulf A.   +5 more
europepmc   +1 more source

Introduction: a linguistic 're-turn' in translation studies? [PDF]

, 2007
Van de Velde, Marc, Vandepitte, Sonia, Vandeweghe, Willy   +2 more
core   +1 more source