Enhancing CAR‐T Cell Efficacy in Solid Tumors by Inhibiting CCL5/VEGF‐Mediated Angiogenesis
This study reveals that CAR‐T cells in solid tumors produce CCL5, which paradoxically induces VEGF and angiogenesis to promote tumor growth. Blocking CCL5/VEGF signaling—through gene knockout, or the CCR5 inhibitor maraviroc—significantly enhances the antitumor efficacy of CAR‑T therapy (the diagram was created in Biorender).
Shishuo Sun +15 more
wiley +1 more source
Factors affecting genetic counseling experiences of foreign residents in Japan: implications for healthcare inclusivity. [PDF]
Nakasato K, Isono M, Kato K.
europepmc +1 more source
LINGUISTIC COMMUNICATION IN THE FORMATION OF PROFESSIONAL COMPETENCE OF FUTURE TRANSLATORS
O. Nazarenko
openalex +1 more source
The Impact of Translators' Cross-Cultural Communication Competence on Sustainable Trade Cooperation in Business Negotiations [PDF]
Miao Ji
openalex +1 more source
The BnTFL1‐BnJAM3‐BnSWEETs Module Orchestrates Seed Storage Reserve Accumulation in Brassica napus
BnaC03.TFL1 and BnaA01.JAM3 form a complex that facilitates the transport of soluble sugars from the seed coat to the embryo by directly activating the expression of BnSWEETs. Furthermore, BnaC03.TFL1 and BnaA01.JAM3 work cooperatively to promote soluble sugar and oil production while suppressing protein deposition.
Jianjun Wang +8 more
wiley +1 more source
Navigating Culture and Crisis: Saudi Mothers' Experiences of Family-Centered Care in Pediatric Intensive Care Units-A Qualitative Study. [PDF]
Alshehri WM +9 more
europepmc +1 more source
In ovarian cancer, MEOX1 activates the SPHK1/S1P pathway to promote both tumor progression and tumor–stroma crosstalk. MEOX1‐dependent signaling drives CAF activation, enhances VEGF‐C expression, and stimulates lymphangiogenesis, ultimately facilitating lymph node metastasis.
Jiajia Li +10 more
wiley +1 more source
Development and Clinical Validation of a Cross-Sex Translator of ECG Drug Responses. [PDF]
Shetty R +5 more
europepmc +1 more source
Translation Competence and Market-oriented Translator Training in a Globalized World
Wei Huangfu
openalex +2 more sources

