Results 61 to 70 of about 132,146 (294)

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Translation and Cognition: Cases of Asymmetry. An Editorial [PDF]

, 2017
This editorial outlines the theoretical and methodological underpinnings of the current special issue, signalling some of the practical implications of the problems investigated.
Alves, Alves, Alvstad, Alvstad, Barlow, Barlow, Brien, Brien, Brien, Brien, Burmakova, Burmakova, Casasanto, Casasanto, Deckert, Deckert, Deckert, Deckert, Deckert, Deckert, Deckert, Deckert, Eckert, Eckert, Ehrensberger, Ehrensberger, Evans, Evans, Evans, Evans, Fausey, Fausey, Fausey, Fausey, Ferreira, Ferreira, Frankish, Frankish, Franz, Franz, Geeraerts, Geeraerts, Geeraerts, Geeraerts, Gentner, Gentner, Givón, Givón, Guy, Guy, Halverson, Halverson, Hansen, Hansen, Hansen, Hansen, Hejwowski, Hejwowski, Ibarretxe, Ibarretxe, Jaeger, Jaeger, Kahneman, Kahneman, Kirby, Kirby, Krupnik, Krupnik, Kubiński, Kubiński, Lakoff, Lakoff, Langacker, Langacker, Langacker, Langacker, Langacker, Langacker, Lewandowska, Lewandowska, Lewandowska, Lewandowska, Massey, Massey, Mees, Mees, Mikołaj Deckert, Muñoz Martin, Muñoz Martin, Muñoz Martin, Muñoz Martin, Piantadosi Steven, Piantadosi Steven, Pullum, Pullum, Pulvermuller, Pulvermuller, Regier, Regier, Risku, Risku, Rojo, Rojo, Rojo, Rojo, Samaniego Fernandez, Samaniego Fernandez, Slobin, Slobin, Steven, Steven, Szarkowska, Szarkowska, Tabakowska, Tabakowska, Tirkkonen, Tirkkonen, Whorf, Whorf, Whyatt, Whyatt, Winawer, Winawer, Wray, Wray, Zipf, Zipf   +126 more
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Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

Molecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann, Eduardo García‐Galea, Alice O'Farrell, Zak Kinsella, Maxime Meylan, Florent Petitprez, Ingrid Arijs, Tom Venken, Hari Ps, Adrian Lärkeryd, Ian Miller, Janick Selves, Nadja Meindl‐Beinker, Fiorella Ruiz‐Pace, Elena Élez, Raquel Comas‐Navarro, Frank Lincoln, Dirk Fey, Gift Nyamundanda, Aoife Nolan, Joern Lewin, Raquel Perez‐Lopez, Jonathan Briody, Kathleen Bennett, Walter Kolch, David Matallanas, Alexander Kel, Enrique Arenas, Joaquín Arribas, Bart Ghesquière, Josep Tabernero, Julie Meilleroux, Deborah McNamara, Ray McDermott, Marvin Lim, Mary O'Reilly, Brian Bird, Lisa Stack, Lucia Moloney, Patrick Morris, Keith Egan, Maciej Milewski, Lars Scheuer, Joachim Behringer, Georg Bolz, Ramon Salazar, Cristina Santos, Andrea Ruiz, Orla Casey, Verena Murphy, Matthias Ebert, Livio Trusolino, Diether Lambrechts, Anguraj Sadanandam, Catherine Sautès‐Fridman, Jochen Prehn, Paolo Nuciforo, Jacques Fieschi, Florence Monville, Darran O'Connor, Wolf Fridman, Annette Byrne   +61 more
wiley   +1 more source

Z dziejów kształtowania się normy przekładu toponimów

Między Oryginałem a Przekładem, 2016
Development of the Norm for Translating Croatian Toponyms Into Polish The article discusses factors that affect translation of Croatian toponyms into Polish in utility (non‑artistic) translation.
Katarzyna Wołek‑San Sebastian
doaj   +1 more source

Employability as an ethos in translator and interpreter training [PDF]

, 2017
‘Employability’ is now a key term in university strategies in the UK and increasingly across Europe. Pressure to implement such strategies can lead to bolted-on rather than embedded activities within academic curricula.
Baines, Roger, Cuminatto, Claire, Drugan, Joanna   +2 more
core   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Didactic Aspects of Translators’ Training Inside the Modern Applied Languages Department [PDF]

Acta Universitatis Sapientiae: Philologica
In this article, we undertake to discuss about the didactic aspects of the translators’ training inside the Applied Modern Languages Department of the Faculty of Letters of Cluj-Napoca.
Adina CORNEA
doaj   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

Technology and translator training

, 2019
There is broad consensus in the literature that anyone who wishes to become a professional translator of pragmatic and technical texts should acquire an understanding of, and an ability to use and critically appraise, contemporary translation technologies.
openaire   +1 more source

Taking statistical machine translation to the student translator [PDF]

, 2012
Despite the growth of statistical machine translation (SMT) research and development in recent years, it remains somewhat out of reach for the translation community where programming expertise and knowledge of statistics tend not to be commonplace. While
Doherty, Stephen, Kenny, Dorothy, Way, Andy   +2 more
core