Results 41 to 50 of about 12,451 (219)
Interpreting the effects of DNA polymerase variants at the structural level
Molecular Oncology, EarlyView.Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
Ikala: Revista de Lenguaje y Cultura, 2010 Objective: to reflect on the role of terminology in accessing specialized knowledge and on the rationale for it being part of translator training in light of the forthcoming implementation of the Degree in Translation and Interpreting in Europe in ...
Natividad Gallardo
doaj
TRANSLATOR TRAINING BY DISTANCE LEARNING — A DUAL APPROACH1
Indonesian Journal of Applied Linguistics, 2015 A variety of approaches have been adopted by institutions of higher education offering programmes in translator training. Some of these approaches are centred on early training; while others on socio-constructivism.
Karnedi Karnedi
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Molecular Oncology, EarlyView.Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen +14 more
wiley +1 more source
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Z dziejów kształtowania się normy przekładu toponimów
Między Oryginałem a Przekładem, 2016 Development of the Norm for Translating Croatian Toponyms Into Polish The article discusses factors that affect translation of Croatian toponyms into Polish in utility (non‑artistic) translation.
Katarzyna Wołek‑San Sebastian
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Molecular Oncology, EarlyView.Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi +14 more
wiley +1 more source
Didactic Aspects of Translators’ Training Inside the Modern Applied Languages Department [PDF]
Acta Universitatis Sapientiae: PhilologicaIn this article, we undertake to discuss about the didactic aspects of the translators’ training inside the Applied Modern Languages Department of the Faculty of Letters of Cluj-Napoca.
Adina CORNEA
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Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae
FEBS Open Bio, EarlyView.Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj +3 more
wiley +1 more source
FEBS Open Bio, EarlyView.In this study, we developed a deep learning method for mitotic figure counting in H&E‐stained whole‐slide images and evaluated its prognostic impact in 13 external validation cohorts from seven different cancer types. Patients with more mitotic figures per mm2 had significantly worse patient outcome in all the studied cancer types except colorectal ...
Joakim Kalsnes +32 more
wiley +1 more source