Results 181 to 190 of about 451,700 (244)

Analysis of complex chromosomal structural variants through optical genome mapping integrated with karyotyping. [PDF]

Front Genet
Zhu X, Zheng H, Wan X, Duan H, Qi Y, Tang W, Yang F, Yu L.   +7 more
europepmc   +1 more source

RAD21L1 Is Sufficient and Effective for Reprogramming Human Sertoli Cells to Phenotypic Spermatogonial Stem Cells Through DNA Methylation and Essential for Male Fertility

Advanced Science, EarlyView.
RAD21L1 is upregulated in human Sertoli cells to be transited to become spermatogonial stem cells by overexpressing DAZ family three genes. RAD21L1 is sufficient and effective for reprogramming Sertoli cells into human spermatogonial stem cells with high safety through DNA methylation.
Caimei He, Yinghong Cui, Wei Chen, Chunyun Li, Zuping He   +4 more
wiley   +1 more source

"A novel approach to understanding the role of TCF3 mutations in childhood B-cell precursor acute lymphoblastic leukemia". [PDF]

Transl Oncol
Lejman M, Ozygała A, Wróblewska K, Zegardło W, Widz P, Żyła M.   +5 more
europepmc   +1 more source

Consecutive Steps of Nucleoside Triphosphate Hydrolysis Are Driving Transport of Precursor Proteins into the Endoplasmic Reticulum [PDF]

, 1992
Klappa, Peter, Lill, Roland, Müller, Günter, Neupert, Walter, Schlenstedt, Gabriel, Wiech, Hans, Zimmermann, Richard   +6 more
core   +1 more source

RELA Ablation Contributes to Progression of Hepatocellular Carcinoma with TP53R249S Mutation and is a Potential Therapeutic Target

Advanced Science, EarlyView.
Genome‐wide CRISPR/Cas9 based screening identified RELA as a key tumor suppressor in TP53R249S‐mutant HCC. Its loss promotes tumorigenesis and metastasis via DVL1‐mediated Wnt/β‐catenin activation, while its agonist betulinic acid suppresses tumor progression.
Zhiping Wu, Zhe Wang, Diwei Zheng, Yongfang Zheng, Zhiwu Jiang, Jiang Lv, Yueqin Zhu, Heng Jia, Ziyuan Duan, Tingjie Yuan, Qiting Wu, Youguo Long, Shouheng Lin, Yao Yao, Georgia Carson, Jean P. Thiery, Kwan Man, Peng Li   +17 more
wiley   +1 more source

Conservation genomics within government led conservation planning: an Australian case study exploring cost and benefit for threatened flora. [PDF]

Ann Bot
Doyle CAT, Cascini M, Yap JS, Matthews H, Hogbin PM, Wilson TC, Mahon E, Brown D, Mulcahy A, Brown R, Rossetto M.   +10 more
europepmc   +1 more source

Protein import into chloroplasts [PDF]

, 1993
Alefsen, Heike, Brennicke, Axel, Kück, Ulrich, Soll, Jürgen   +3 more
core   +1 more source

Life Factors and Melanoma: From the Macroscopic State to the Molecular Mechanism

Advanced Science, EarlyView.
Melanoma, an aggressive skin cancer, arises from dynamic interactions between genetic, environmental, and lifestyle factors. This review explores how age, gender, obesity, diet, exercise, smoking, alcohol, UV exposure, circadian rhythms, and medications influence melanoma risk and progression.
Hanbin Wang, Hengxiang Zhang, Yuqi Zhou, Chunying Li, Weinan Guo   +4 more
wiley   +1 more source

Infertility Due to a Novel Variant of a Balanced Y;1 Translocation: A Case Report. [PDF]

Cureus
Magnuson S, Doney K, Wesemann LB, Gross K.   +3 more
europepmc   +1 more source

Cisgenics - Facilitating the second green revolution in India by improved traditional plant breeding [PDF]

, 2008
Jacobsen, E., Nataraja, K.N.
core   +1 more source