Results 271 to 280 of about 3,324,185 (335)

HPD is an m6A Methyltransferase that Protects Colorectal Cancer Cells from Ferroptotic Cell Death by m6A Methylating SLC7A11/GPX4

Advanced Science, EarlyView.
This study reveals that the tyrosine metabolic enzyme HPD functions as a previously uncharacterized, METTL3‐independent m6A methyltransferase. It promotes colorectal tumor progression by coordinately regulating the SLC7A11/GPX4 axis to suppress ferroptosis.
Jiyan Wang, Xintong Dai, Huanle Liu, Saiwei Hua, Hongkai Chang, Huanran Sun, Mingming Sun, Huifang Zhao, Kemin Ni, Fei Xie, Yaya Qiao, Qingle Gao, Chenxi Yu, Qijun Zhang, Jianshuang Guo, Chunze Zhang, Shuai Zhang, Changliang Shan   +17 more
wiley   +1 more source

Symptomatic anomalous right coronary artery in mother and daughter, a case report. [PDF]

J Cardiothorac Surg
Nahal C, Borden N, Johnson E, Faber C.
europepmc   +1 more source

Cancer Cell‐Intrinsic Cholesterol Induces Lipid‐Associated Macrophage Differentiation via SP1 Palmitoylation to Promote Prostate Cancer Progression

Advanced Science, EarlyView.
Cancer cell‐intrinsic cholesterol promotes the S‐palmitoylation of SP1, increasing its nuclear translocation and driving the transcription and secretion of MDK, which in turn facilitates the differentiation of macrophages into a lipid‐associated phenotype.
Shirong Peng, Weilong Lin, Zean Li, Ruilin Zhuang, Shengmeng Peng, Bingheng Li, Bingliang Chen, Yong Luo, Yuan Ou, Wei Zhuang, Tao Du, Kaiwen Li, Hai Huang   +12 more
wiley   +1 more source

Sex-determining Region of Y-gene Translocation and 46,XX Testicular Disorders of Sex Development: Cytogenetic and Molecular Insights into Male Infertility. [PDF]

J Hum Reprod Sci
Priya PK, Patel H, Dalal D, Shah A.
europepmc   +1 more source

Postmortem Microbiology in Forensic Diagnostics: Interpretation of Infectious Causes of Death and Emerging Applications. [PDF]

Diagnostics (Basel)
Camatti J, Bonasoni MP, Santunione AL, Cecchi R, Radheshi E, Carretto E.   +5 more
europepmc   +1 more source

Gametocidal genes: biological mechanisms owing to hybrid dysgenesis in crop breeding, challenges and innovation. [PDF]

Ann Bot
Walter N, King I, King J, Grewal S.
europepmc   +1 more source

Reinforced Defenses: <i>R</i>-Genes, PTI, and ETI in Modern Wheat Breeding for Blast Resistance. [PDF]

Int J Mol Sci
Hossain MM, Sultana F, Mostafa M, Khan I, Tran LP, Mostofa MG.   +5 more
europepmc   +1 more source

Balanced Translocations Involving the <i>DMD</i> Gene as a Cause of Muscular Dystrophy in Female Children: A Description of Three Cases. [PDF]

Int J Mol Sci
Vorontsova EO, Murtazina A, Zinina E, Polyakov AV, Sumina M, Rybakova OA, Vlodavets D, Kazakov D, Suvorova Y, Sharkova IV, Demina NA, Repina SA, Bulanova VA, Antonova M, Dadali E, Marakhonov AV, Shilova NV, Kutsev SI, Shchagina OA.   +18 more
europepmc   +1 more source